Description |
ADAM metallopeptidase domain 12 |
protein kinase C and casein kinase substrate in neurons 3 |
Image |
No pdb structure |
No pdb structure |
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
|
|
Diseases |
|
|
GWAS |
- Blood protein levels ( 30072576)
- Endometrial cancer ( 24096698)
- Extremely high intelligence ( 29731509)
- Heel bone mineral density ( 30598549)
- Intraocular pressure ( 30054594)
- Itch intensity from mosquito bite ( 28199695)
- Loneliness ( 27629369)
- Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000)
- Mild influenza (H1N1) infection ( 26379185)
- Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070 27021288)
- Placental abruption ( 29884306)
- Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
- Visceral fat ( 22589738)
|
- Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717)
- Autism spectrum disorder or schizophrenia ( 28540026)
- Waist-to-hip ratio adjusted for body mass index ( 26785701)
|
Interacting Genes |
40 interacting genes:
ACTN2
ADAMTSL4
CYSRT1
EGF
ESM1
FHL5
FSTL3
GRB2
GUCD1
HOXA1
IGFBP3
IGFBP5
KRT83
KRTAP1-1
KRTAP1-3
KRTAP10-8
KRTAP12-2
KRTAP3-1
KRTAP3-2
KRTAP4-12
KRTAP5-6
KRTAP5-9
KRTAP6-2
KRTAP9-2
KRTAP9-8
LCE5A
MAPKBP1
NBPF19
NOTCH2NLA
OTX1
PACSIN3
PIK3R1
RECK
SH3D19
SLC15A2
SPRY1
SPRY4
SRC
TFAP2D
YES1
|
23 interacting genes:
ADAM12
ADAM15
ASAP1
ASAP2
ATXN7L2
CLNK
DNM1
ITSN1
KRTAP12-2
LGALS13
PACSIN1
PACSIN2
PAK2
RAF1
SMARCD1
SOS1
SOS2
SPRY2
SYNJ1
TERF2IP
TNPO2
TRPV4
WASL
|
Entrez ID |
8038 |
29763 |
HPRD ID |
04092 |
05937 |
Ensembl ID |
ENSG00000148848
|
ENSG00000165912
|
Uniprot IDs |
A8K6G4
O43184
U5NE98
|
Q9UKS6
|
PDB IDs |
|
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
|
Tagcloud (Difference) ? |
|
|
Tagcloud (Intersection) ? |
|