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CCDC6 and ATF2
Data Source:
BioGRID
(pull down)
CCDC6
ATF2
Description
coiled-coil domain containing 6
activating transcription factor 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Cytoskeleton
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrial Outer Membrane
Site Of Double-strand Break
H4 Histone Acetyltransferase Complex
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
SH3 Domain Binding
Identical Protein Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Activating Transcription Factor Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
DNA-binding Transcription Factor Activity
Histone Acetyltransferase Activity
Protein Binding
CAMP Response Element Binding Protein Binding
H4 Histone Acetyltransferase Activity
Protein Kinase Binding
CAMP Response Element Binding
H2B Histone Acetyltransferase Activity
Protein-containing Complex Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Cytoskeleton Organization
Biological_process
Negative Regulation Of Transcription By RNA Polymerase II
Outflow Tract Morphogenesis
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Response To Osmotic Stress
Cellular Response To DNA Damage Stimulus
Response To Water Deprivation
Positive Regulation Of Gene Expression
Negative Regulation Of Angiogenesis
Intra-S DNA Damage Checkpoint
Positive Regulation Of Transforming Growth Factor Beta2 Production
Positive Regulation Of Neuron Apoptotic Process
Histone H4 Acetylation
Histone H2B Acetylation
Fat Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Epithelial Cell Proliferation
Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of DNA-binding Transcription Factor Activity
Adipose Tissue Development
Amelogenesis
Positive Regulation Of Cardiac Muscle Myoblast Proliferation
Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Pathways
Transcriptional activation of mitochondrial biogenesis
HATs acetylate histones
Circadian Clock
Activation of the AP-1 family of transcription factors
TP53 Regulates Transcription of DNA Repair Genes
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Estrogen-dependent gene expression
NGF-stimulated transcription
NGF-stimulated transcription
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK4 (GCN2) to amino acid deficiency
Drugs
Pseudoephedrine
Diseases
Thyroid cancer
GWAS
Alopecia areata (
25608926
)
Heel bone mineral density (
30598549
)
Metabolite levels (
23823483
)
Monocyte percentage of white cells (
32888494
)
Pulse pressure (
27841878
)
Systolic blood pressure (
27841878
)
Intake of total sugars (
31005972
)
Metabolite levels (
23823483
)
Interacting Genes
32 interacting genes:
ATF2
ATF5
CCDC136
CCDC33
CENPQ
CREB1
CSNK2A1
CYTH4
FBXW7
GAS8
LHX3
LRSAM1
LUZP4
MAPK3
MAPK7
MEOX2
MTUS2
PAX6
PIN1
PPP4C
SH3RF1
SNAPC1
SORBS3
TFIP11
TRIM14
UBE2I
WAC
ZNF250
ZNF354C
ZNF620
ZNF774
ZNF835
63 interacting genes:
APP
AR
ATF3
ATF4
ATF7
BACH1
BANP
BATF
CCDC6
CCND1
CEBPA
CEBPB
CEBPG
CENPQ
CREB5
CSNK2A1
CSNK2A2
DDIT3
DNMT3L
EDF1
ETS1
EXOSC8
FOS
FOSB
FOSL1
FOSL2
GTF2F2
H2BC21
HMGA1
IRF2BP1
JDP2
JUN
KIFC3
LHX8
MACROH2A1
MAPK1
MAPK10
MAPK11
MAPK13
MAPK14
MAPK8
MAPK9
MAPKAPK5
MLH1
NBN
NCOA6
PIAS2
PML
PRKCE
RB1
RNF4
RPS6KA5
RUVBL2
SMAD3
SMAD4
SPOPL
SRA1
SUMO1
THRB
UBE2I
UTF1
XPO1
YY1
Entrez ID
8030
1386
HPRD ID
09064
00443
Ensembl ID
ENSG00000108091
ENSG00000115966
Uniprot IDs
Q05CP8
Q16204
A4D7V5
P15336
PDB IDs
1BHI
1T2K
4H36
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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