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NR4A3 and ALPP
Data Source:
BioGRID
(two hybrid)
NR4A3
ALPP
Description
nuclear receptor subfamily 4 group A member 3
alkaline phosphatase, placental
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Anchored Component Of Membrane
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Steroid Hormone Receptor Activity
Nuclear Receptor Activity
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Glucocorticoid Receptor Binding
CAMP Response Element Binding
Protein Homodimerization Activity
Magnesium Ion Binding
Alkaline Phosphatase Activity
Protein Binding
Zinc Ion Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Gastrulation
Pyruvate Oxidation
Positive Regulation Of Cardiac Muscle Hypertrophy
Positive Regulation Of Glucose Transmembrane Transport
Intracellular Receptor Signaling Pathway
Animal Organ Regeneration
Positive Regulation Of Mast Cell Cytokine Production
Common Myeloid Progenitor Cell Proliferation
Positive Regulation Of Mast Cell Activation By Fc-epsilon Receptor Signaling Pathway
Mast Cell Degranulation
Steroid Hormone Mediated Signaling Pathway
Cellular Response To Leptin Stimulus
Cellular Respiration
Fat Cell Differentiation
Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Fatty Acid Oxidation
Platelet-derived Growth Factor Receptor Signaling Pathway
Regulation Of Smooth Muscle Cell Proliferation
Positive Regulation Of Smooth Muscle Cell Proliferation
Positive Regulation Of Epithelial Cell Proliferation
Regulation Of Type B Pancreatic Cell Proliferation
Cellular Response To Corticotropin-releasing Hormone Stimulus
Cellular Response To Catecholamine Stimulus
Energy Homeostasis
Positive Regulation Of Monocyte Aggregation
Negative Regulation Of Hydrogen Peroxide-induced Neuron Death
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration
Positive Regulation Of Feeding Behavior
Dephosphorylation
Pathways
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Intra-Golgi traffic
Drugs
Dasatinib
Calcium
METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER
Diseases
Extraskeletal myxoid chondrosarcoma
GWAS
Dental caries (
23064961
)
Depression in smokers (
30219690
)
Eosinophil percentage of white cells (
32888494
)
Lung cancer (
28604730
)
Systemic lupus erythematosus (
33536424
)
Blood protein levels (
30072576
)
Height (
19570815
)
Refractive error (
32231278
)
Interacting Genes
43 interacting genes:
ADAMTSL4
ALPP
CDKN2D
CHRD
COPS5
CYP21A2
CYSRT1
EFEMP1
HSD3B7
KPRP
KRTAP10-1
KRTAP10-5
KRTAP10-8
KRTAP12-3
KRTAP12-4
KRTAP4-11
KRTAP4-2
KRTAP4-4
KRTAP5-11
KRTAP5-3
KRTAP5-6
KRTAP5-9
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-8
LCE2B
LCE2D
MACO1
NECTIN2
PCSK5
PIN1
RECK
RPS6KA1
SIX3
SMOC1
TRIM28
TSPAN4
UBE3A
VASN
VHL
VWC2L
ZNF330
42 interacting genes:
ADAMTSL4
ALPG
CRCT1
CREB5
CXCL5
CYSRT1
FBXO34
GEMIN4
GPLD1
GSC2
HOXA1
IGFBP6
KRTAP1-1
KRTAP1-3
KRTAP10-3
KRTAP10-8
KRTAP4-12
KRTAP5-9
LATS1
LCE1D
LCE1E
LCE1F
LCE2C
LCE3A
LCE3B
LCE3C
LCE3D
LCE3E
LCE5A
LELP1
MEOX2
NBPF19
NLGN3
NOTCH2NLA
NR4A3
OTX1
PIGK
POU4F2
RGS19
RGS20
SMCP
TGM1
Entrez ID
8013
250
HPRD ID
02766
01379
Ensembl ID
ENSG00000119508
ENSG00000163283
Uniprot IDs
A0A024R168
Q92570
B2R7C7
P05187
PDB IDs
1EW2
1ZEB
1ZED
1ZEF
2GLQ
3MK0
3MK1
3MK2
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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