ALPP and LCE3C

Data Source:
BioGRID (two hybrid)

		ALPP	LCE3C
Description		alkaline phosphatase, placental	late cornified envelope 3C
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane Anchored Component Of Membrane
	Molecular Function	Magnesium Ion Binding Alkaline Phosphatase Activity Protein Binding Zinc Ion Binding	Protein Binding
	Biological Process	Dephosphorylation	Keratinization Killing Of Cells Of Other Organism Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways		Intra-Golgi traffic	Formation of the cornified envelope
Drugs		Calcium METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER
Diseases
GWAS		Blood protein levels ( 30072576) Height ( 19570815) Refractive error ( 32231278)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		42 interacting genes: ADAMTSL4 ALPG CRCT1 CREB5 CXCL5 CYSRT1 FBXO34 GEMIN4 GPLD1 GSC2 HOXA1 IGFBP6 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP4-12 KRTAP5-9 LATS1 LCE1D LCE1E LCE1F LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE5A LELP1 MEOX2 NBPF19 NLGN3 NOTCH2NLA NR4A3 OTX1 PIGK POU4F2 RGS19 RGS20 SMCP TGM1	55 interacting genes: ADAMTSL4 ALPP CHIC2 CYP21A2 CYSRT1 EFEMP2 GRN HOXA1 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 LCE1B MDFI NBPF19 NOTCH2NLA PCSK5 PLSCR1 RGS17 RGS20 SPRY1 SPRY2 TRIM42 TSPAN4 ZNF655
Entrez ID		250	353144
HPRD ID		01379	17262
Ensembl ID		ENSG00000163283	ENSG00000244057
Uniprot IDs		B2R7C7 P05187	Q5T5A8
PDB IDs		1EW2 1ZEB 1ZED 1ZEF 2GLQ 3MK0 3MK1 3MK2
Enriched GO Terms of Interacting Partners?
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