ALPP and RGS19

Data Source:
BioGRID (two hybrid)

		ALPP	RGS19
Description		alkaline phosphatase, placental	regulator of G protein signaling 19
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GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane Anchored Component Of Membrane	Golgi Apparatus Plasma Membrane Brush Border Membrane Clathrin-coated Vesicle Membrane Raft
	Molecular Function	Magnesium Ion Binding Alkaline Phosphatase Activity Protein Binding Zinc Ion Binding	G-protein Alpha-subunit Binding GTPase Activity Protein Binding
	Biological Process	Dephosphorylation	Autophagy G Protein-coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Negative Regulation Of Signal Transduction Response To Ethanol
Pathways		Intra-Golgi traffic	G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events
Drugs		Calcium METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER
Diseases
GWAS		Blood protein levels ( 30072576) Height ( 19570815) Refractive error ( 32231278)	Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Chronic kidney disease ( 31152163) Coronary artery disease ( 33020668) Estimated glomerular filtration rate ( 31152163) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Systolic blood pressure ( 30578418)
Interacting Genes		42 interacting genes: ADAMTSL4 ALPG CRCT1 CREB5 CXCL5 CYSRT1 FBXO34 GEMIN4 GPLD1 GSC2 HOXA1 IGFBP6 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP4-12 KRTAP5-9 LATS1 LCE1D LCE1E LCE1F LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE5A LELP1 MEOX2 NBPF19 NLGN3 NOTCH2NLA NR4A3 OTX1 PIGK POU4F2 RGS19 RGS20 SMCP TGM1	25 interacting genes: ALPP CATSPER1 CSNK2A1 CSNK2A2 GDE1 GIPC1 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 KRTAP5-6 LCE4A MAPK1 MAPK6 NUFIP2 OPRL1 OSTM1 OTX1 POU4F2 PRKCA PSMA1 TGFBR1 VASN
Entrez ID		250	10287
HPRD ID		01379	05461
Ensembl ID		ENSG00000163283	ENSG00000171700
Uniprot IDs		B2R7C7 P05187	B4DP94 P49795
PDB IDs		1EW2 1ZEB 1ZED 1ZEF 2GLQ 3MK0 3MK1 3MK2	1CMZ
Enriched GO Terms of Interacting Partners?
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