NR4A3 and KRTAP10-5

Data Source:
BioGRID (two hybrid)

		NR4A3	KRTAP10-5
Description		nuclear receptor subfamily 4 group A member 3	keratin associated protein 10-5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex	Cytosol Keratin Filament
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Steroid Hormone Receptor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Glucocorticoid Receptor Binding CAMP Response Element Binding Protein Homodimerization Activity	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Gastrulation Pyruvate Oxidation Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Glucose Transmembrane Transport Intracellular Receptor Signaling Pathway Animal Organ Regeneration Positive Regulation Of Mast Cell Cytokine Production Common Myeloid Progenitor Cell Proliferation Positive Regulation Of Mast Cell Activation By Fc-epsilon Receptor Signaling Pathway Mast Cell Degranulation Steroid Hormone Mediated Signaling Pathway Cellular Response To Leptin Stimulus Cellular Respiration Fat Cell Differentiation Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Fatty Acid Oxidation Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Epithelial Cell Proliferation Regulation Of Type B Pancreatic Cell Proliferation Cellular Response To Corticotropin-releasing Hormone Stimulus Cellular Response To Catecholamine Stimulus Energy Homeostasis Positive Regulation Of Monocyte Aggregation Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Positive Regulation Of Feeding Behavior	Keratinization
Pathways		RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs		Dasatinib
Diseases		Extraskeletal myxoid chondrosarcoma
GWAS		Dental caries ( 23064961) Depression in smokers ( 30219690) Eosinophil percentage of white cells ( 32888494) Lung cancer ( 28604730) Systemic lupus erythematosus ( 33536424)
Interacting Genes		43 interacting genes: ADAMTSL4 ALPP CDKN2D CHRD COPS5 CYP21A2 CYSRT1 EFEMP1 HSD3B7 KPRP KRTAP10-1 KRTAP10-5 KRTAP10-8 KRTAP12-3 KRTAP12-4 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP5-11 KRTAP5-3 KRTAP5-6 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE2B LCE2D MACO1 NECTIN2 PCSK5 PIN1 RECK RPS6KA1 SIX3 SMOC1 TRIM28 TSPAN4 UBE3A VASN VHL VWC2L ZNF330	143 interacting genes: ADAMTSL4 AEN ALDH3B1 AMOTL2 BCL6B BMP7 BYSL C11orf87 C17orf50 CARD9 CATSPER1 CHRD CNNM3 CREB5 CYSRT1 DHX57 ECE1 EIF4E2 ENKD1 FAM74A4 FAM76B FARS2 FBXO34 FCHO1 GATA1 GLIDR GLRX3 GNE GOLGA8EP GPRIN2 HHEX HOXA1 HPCAL1 KRTAP1-3 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP13-1 KRTAP13-2 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1B LCE1C LCE1D LCE1E LCE2A LCE2C LCE2D LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LIMS2 LUZP4 MEOX2 MOBP MT1DP MXI1 NAA10 NBPF19 NECTIN2 NOTCH2NLA NPDC1 NR4A1 NR4A3 NTAQ1 NUFIP2 OTX1 POM121L8P POU4F2 PRKAB2 PRKAG1 PRR13 RBP3 SCNM1 SHFL SLC23A1 SLC6A20 SMCP SPACA9 SPATA3 SPRY1 SPRY2 STK16 TBC1D16 THAP10 TNP2 TNS2 TRIM42 TRPV6 TULP3 TXNDC5 TYMSOS UTP23 WT1 WT1-AS YY1 ZBTB24 ZBTB48 ZFYVE21 ZNF124 ZNF20 ZNF264 ZNF273 ZNF286A ZNF32 ZNF320 ZNF329 ZNF34 ZNF417 ZNF433 ZNF439 ZNF440 ZNF559 ZNF572 ZNF578 ZNF587 ZNF670 ZNF679 ZNF696 ZNF697 ZNF707 ZNF785 ZNF792 ZSCAN21 ZSCAN26
Entrez ID		8013	386680
HPRD ID		02766	11191
Ensembl ID		ENSG00000119508	ENSG00000241123
Uniprot IDs		A0A024R168 Q92570
PDB IDs
Enriched GO Terms of Interacting Partners?
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