BAIAP2L2 and POLE2

Data Source:
BioGRID (two hybrid)

		BAIAP2L2	POLE2
Description		BAR/IMD domain containing adaptor protein 2 like 2	DNA polymerase epsilon 2, accessory subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Vesicle Membrane Cytoplasmic Vesicle Membrane Cell-cell Contact Zone Clathrin Complex	Nucleoplasm Epsilon DNA Polymerase Complex Nuclear Body Intracellular Membrane-bounded Organelle
	Molecular Function	Phospholipid Binding	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding
	Biological Process	Plasma Membrane Organization Positive Regulation Of Actin Filament Polymerization Actin Filament Bundle Assembly Actin Crosslink Formation Membrane Organization Positive Regulation Of Actin Cytoskeleton Reorganization	G1/S Transition Of Mitotic Cell Cycle DNA Replication DNA-dependent DNA Replication DNA Replication Initiation DNA Repair Telomere Maintenance Via Semi-conservative Replication Error-prone Translesion Synthesis
Pathways			Recognition of DNA damage by PCNA-containing replication complex PCNA-Dependent Long Patch Base Excision Repair Termination of translesion DNA synthesis HDR through Homologous Recombination (HRR) Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER DNA replication initiation Activation of the pre-replicative complex
Drugs			Cladribine
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cutaneous malignant melanoma ( 32341527)
Interacting Genes		6 interacting genes: ABI3 FAM9B GABPB1 GLYCTK GRXCR1 POLE2	19 interacting genes: AGFG1 BAIAP2L2 EEF1A1 ERG28 EXOSC4 KAT5 MAPRE1 PKM POLE POLE4 REL SAP18 SORBS3 TBX15 TLE1 TRIM27 UBQLN2 ZBED1 ZNF620
Entrez ID		80115	5427
HPRD ID		07997	16007
Ensembl ID		ENSG00000128298	ENSG00000100479
Uniprot IDs		Q6UXY1	P56282
PDB IDs			2V6Z 5VBN
Enriched GO Terms of Interacting Partners?
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