TCF19 and RHOH

Data Source:
BioGRID (two hybrid)

		TCF19	RHOH
Description		transcription factor 19	ras homolog family member H
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Immunological Synapse Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle
	Molecular Function	DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	GTPase Activity GTPase Inhibitor Activity Protein Binding GTP Binding Kinase Inhibitor Activity Protein Kinase Binding Small GTPase Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Gene Expression	Regulation Of Transcription, DNA-templated Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Motor Neuron Axon Guidance Regulation Of Cell Shape Rac Protein Signal Transduction Cell Projection Assembly T Cell Differentiation Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Kinase Activity Negative Regulation Of GTPase Activity Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Engulfment Of Apoptotic Cell Mast Cell Activation Positive Regulation Of T Cell Differentiation Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Neutrophil Migration
Pathways			Rho GTPase cycle
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Chronic hepatitis B infection ( 25802187 23760081) Idiopathic membranous nephropathy ( 21323541) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Marginal zone lymphoma ( 25569183) Multiple myeloma ( 23955597) Night sleep phenotypes ( 27126917) Refractive error ( 32231278) Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) ( 21912425) Type 2 diabetes ( 24509480 30718926) Ulcerative colitis ( 28067908) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)	Graves' disease ( 21841780) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		19 interacting genes: APP BLZF1 CEP76 DNAJA3 GOLGA2 H3-4 H4-16 HOXA1 HSF2BP LZTR1 NFKBID NOXA1 PDLIM7 PFDN5 PRKAB2 RHOH TRIB3 UBE3A ZNF474	23 interacting genes: ARHGDIA ARHGDIB ARHGDIG BANP CCNH FAM90A1 GDI1 IQUB ITGB1BP1 KANK2 KCNH2 LRIF1 MBLAC1 MTX2 PLEKHA7 RIPPLY1 SCNM1 SORL1 SUOX TCF19 TGFBR1 UTP14A XPNPEP1
Entrez ID		6941	399
HPRD ID		15986	03616
Ensembl ID		ENSG00000137310	ENSG00000168421
Uniprot IDs		A0A1U9X8M7 Q9Y242	Q15669 Q6ICP4
PDB IDs
Enriched GO Terms of Interacting Partners?
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