UBA5 and UFM1

Data Source:
BioGRID (enzymatic study)

		UBA5	UFM1
Description		ubiquitin like modifier activating enzyme 5	ubiquitin fold modifier 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle	Nucleus Cytoplasm Endoplasmic Reticulum
	Molecular Function	Protein Binding ATP Binding Zinc Ion Binding Protein Homodimerization Activity UFM1 Activating Enzyme Activity	Protein Binding
	Biological Process	Protein Phosphopantetheinylation Erythrocyte Differentiation Megakaryocyte Differentiation Protein Modification By Small Protein Conjugation Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Neuromuscular Process Reticulophagy Protein Ufmylation Protein K69-linked Ufmylation	Brain Development Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Apoptotic Process Reticulophagy Protein Ufmylation Protein K69-linked Ufmylation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Low vWF levels ( 26486471) Schizophrenia ( 30285260)
Interacting Genes		7 interacting genes: APEH GABARAPL2 PKD1P1 UBE2D2 UBE2L3 UFC1 UFM1	16 interacting genes: ARHGDIA ARHGDIB DIABLO GSK3B INCA1 KCTD21 RPS6KA6 TSC22D2 UBA5 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2W
Entrez ID		79876	51569
HPRD ID		15598	15644
Ensembl ID		ENSG00000081307	ENSG00000120686
Uniprot IDs		Q9GZZ9	P61960
PDB IDs		3GUC 3H8V 5HKH 5IA8 5IAA 5L95 6H77 6H78 6H8C	1WXS 5HKH 5IA7 5IA8 5IAA 5L95 6H77
Enriched GO Terms of Interacting Partners?
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