UBA5 and UFC1

Data Source:
BioGRID (enzymatic study)

		UBA5	UFC1
Description		ubiquitin like modifier activating enzyme 5	ubiquitin-fold modifier conjugating enzyme 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle	Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding Zinc Ion Binding Protein Homodimerization Activity UFM1 Activating Enzyme Activity	Protein Binding UFM1 Conjugating Enzyme Activity UFM1 Transferase Activity
	Biological Process	Protein Phosphopantetheinylation Erythrocyte Differentiation Megakaryocyte Differentiation Protein Modification By Small Protein Conjugation Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Neuromuscular Process Reticulophagy Protein Ufmylation Protein K69-linked Ufmylation	Brain Development Protein Phosphopantetheinylation Response To Endoplasmic Reticulum Stress Reticulophagy Protein Ufmylation Protein K69-linked Ufmylation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		7 interacting genes: APEH GABARAPL2 PKD1P1 UBE2D2 UBE2L3 UFC1 UFM1	4 interacting genes: ANKRD11 GEMIN4 NTAQ1 UBA5
Entrez ID		79876	51506
HPRD ID		15598	15643
Ensembl ID		ENSG00000081307	ENSG00000143222
Uniprot IDs		Q9GZZ9	Q9Y3C8
PDB IDs		3GUC 3H8V 5HKH 5IA8 5IAA 5L95 6H77 6H78 6H8C	2K07 2Z6O 2Z6P 3EVX
Enriched GO Terms of Interacting Partners?
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