UBA5 and APEH

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UBA5	APEH
Description		ubiquitin like modifier activating enzyme 5	acylaminoacyl-peptide hydrolase
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle	Extracellular Region Cytosol Nuclear Membrane Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding ATP Binding Zinc Ion Binding Protein Homodimerization Activity UFM1 Activating Enzyme Activity	RNA Binding Serine-type Endopeptidase Activity Protein Binding Omega Peptidase Activity Identical Protein Binding
	Biological Process	Protein Phosphopantetheinylation Erythrocyte Differentiation Megakaryocyte Differentiation Protein Modification By Small Protein Conjugation Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Neuromuscular Process Reticulophagy Protein Ufmylation Protein K69-linked Ufmylation	Translational Termination Proteolysis Neutrophil Degranulation Amyloid-beta Metabolic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Neutrophil degranulation Eukaryotic Translation Termination
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Blood protein levels ( 29875488 28240269) Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Extremely high intelligence ( 29520040) Feeling tense ( 29500382) Feeling worry ( 29500382) Household income ( 31844048) Inflammatory bowel disease ( 28067908) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908 21297633)
Interacting Genes		7 interacting genes: APEH GABARAPL2 PKD1P1 UBE2D2 UBE2L3 UFC1 UFM1	5 interacting genes: IST1 LGALS8 SHBG TMEM62 UBA5
Entrez ID		79876	327
HPRD ID		15598	00034
Ensembl ID		ENSG00000081307	ENSG00000164062
Uniprot IDs		Q9GZZ9	P13798
PDB IDs		3GUC 3H8V 5HKH 5IA8 5IAA 5L95 6H77 6H78 6H8C
Enriched GO Terms of Interacting Partners?
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