UFM1 and ARHGDIB

Data Source:
BioGRID (two hybrid)

		UFM1	ARHGDIB
Description		ubiquitin fold modifier 1	Rho GDP dissociation inhibitor beta
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GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum	Cytoplasm Cytosol Cytoskeleton Membrane Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Protein Binding	GTPase Activity Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Brain Development Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Apoptotic Process Reticulophagy Protein Ufmylation Protein K69-linked Ufmylation	Negative Regulation Of Cell Adhesion Rho Protein Signal Transduction Multicellular Organism Development Regulation Of Rho Protein Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Cellular Response To Redox State Negative Regulation Of Trophoblast Cell Migration Regulation Of Actin Cytoskeleton Reorganization
Pathways			Rho GTPase cycle
Drugs
Diseases
GWAS		Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Low vWF levels ( 26486471) Schizophrenia ( 30285260)
Interacting Genes		16 interacting genes: ARHGDIA ARHGDIB DIABLO GSK3B INCA1 KCTD21 RPS6KA6 TSC22D2 UBA5 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2W	13 interacting genes: ANKRD1 APP CASP3 CDC42 EZR RAC1 RAC2 RAC3 RHOA RHOH UBE3A UFM1 VAV1
Entrez ID		51569	397
HPRD ID		15644	04162
Ensembl ID		ENSG00000120686	ENSG00000111348
Uniprot IDs		P61960	A0A024RAS5 P52566
PDB IDs		1WXS 5HKH 5IA7 5IA8 5IAA 5L95 6H77	1DS6 5H1D
Enriched GO Terms of Interacting Partners?
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