UFC1 and UBA5

Data Source:
BioGRID (enzymatic study)

		UFC1	UBA5
Description		ubiquitin-fold modifier conjugating enzyme 1	ubiquitin like modifier activating enzyme 5
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GO Annotations	Cellular Component	Extracellular Exosome	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding UFM1 Conjugating Enzyme Activity UFM1 Transferase Activity	Protein Binding ATP Binding Zinc Ion Binding Protein Homodimerization Activity UFM1 Activating Enzyme Activity
	Biological Process	Brain Development Protein Phosphopantetheinylation Response To Endoplasmic Reticulum Stress Reticulophagy Protein Ufmylation Protein K69-linked Ufmylation	Protein Phosphopantetheinylation Erythrocyte Differentiation Megakaryocyte Differentiation Protein Modification By Small Protein Conjugation Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Neuromuscular Process Reticulophagy Protein Ufmylation Protein K69-linked Ufmylation
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		4 interacting genes: ANKRD11 GEMIN4 NTAQ1 UBA5	7 interacting genes: APEH GABARAPL2 PKD1P1 UBE2D2 UBE2L3 UFC1 UFM1
Entrez ID		51506	79876
HPRD ID		15643	15598
Ensembl ID		ENSG00000143222	ENSG00000081307
Uniprot IDs		Q9Y3C8	Q9GZZ9
PDB IDs		2K07 2Z6O 2Z6P 3EVX	3GUC 3H8V 5HKH 5IA8 5IAA 5L95 6H77 6H78 6H8C
Enriched GO Terms of Interacting Partners?
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