USP49 and PTCD2

Data Source:
BioGRID (two hybrid)

		USP49	PTCD2
Description		ubiquitin specific peptidase 49	pentatricopeptide repeat domain 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Mitochondrion
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Histone Binding	RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination Protein Phosphopantetheinylation Histone H2B Conserved C-terminal Lysine Deubiquitination	Kidney Development Liver Development MRNA Processing Mitochondrion Organization Multicellular Organism Development Regulation Of Gene Expression Muscle Fiber Development Regulation Of MRNA Processing Ventricular Cardiac Muscle Tissue Morphogenesis
Pathways		Ub-specific processing proteases
Drugs
Diseases
GWAS		Cutaneous psoriasis ( 26626624) Mean corpuscular hemoglobin ( 32888494 20139978) Mean corpuscular volume ( 23263863 32888494 20139978 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494) Platelet distribution width ( 32888494) Red blood cell count ( 32888494 20139978 27863252) Reticulocyte count ( 32888494) Skin aging (microtopography measurement) ( 28502801) Sleep duration (short sleep) ( 30846698)	Apolipoprotein A1 levels ( 32203549) Asthma ( 32296059) Asthma (childhood onset) ( 31036433) Glaucoma ( 31959993) Intraocular pressure ( 29617998 29785010 31959993 30054594) Pulse pressure ( 27841878) Refractive error ( 32231278)
Interacting Genes		12 interacting genes: FKBP5 H2BC21 MED17 MED18 MED8 NAMPT PTCD2 RBCK1 STING1 TP53 TRIM35 ZNF774	4 interacting genes: MID1 MID2 TRIM32 USP49
Entrez ID		25862	79810
HPRD ID		10075	15193
Ensembl ID		ENSG00000164663	ENSG00000049883
Uniprot IDs		Q70CQ1	A0A024RAM6 B3KPU6 B7Z8R2 F6S289 Q8WV60
PDB IDs
Enriched GO Terms of Interacting Partners?
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