TBC1D17 and ASCC2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TBC1D17	ASCC2
Description		TBC1 domain family member 17	activating signal cointegrator 1 complex subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Autophagosome Cytosol Recycling Endosome	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex
	Molecular Function	GTPase Activator Activity Protein Binding	Protein Binding Ubiquitin Binding
	Biological Process	Intracellular Protein Transport Autophagy Retrograde Transport, Endosome To Golgi Activation Of GTPase Activity Regulation Of Cilium Assembly	DNA Dealkylation Involved In DNA Repair Regulation Of Transcription, DNA-templated
Pathways		TBC/RABGAPs	ALKBH3 mediated reversal of alkylation damage
Drugs
Diseases
GWAS			Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) Hemoglobin levels ( 32327693) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		19 interacting genes: ASCC2 CALCOCO1 CCT5 CDKN2D DHX29 FBL GABARAPL1 GPS1 GTF3C1 MAP1LC3A MAP1LC3B NIPSNAP1 OPTN RAB1A RAB5A RAB5B RAB5C SLC1A5 TAX1BP1	41 interacting genes: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KATNAL1 KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 PRPF18 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1
Entrez ID		79735	84164
HPRD ID		15471	16515
Ensembl ID		ENSG00000104946	ENSG00000100325
Uniprot IDs		Q9HA65	A0A024R1E1 A0A024R1F9 Q9H1I8
PDB IDs			2DI0 6YXQ
Enriched GO Terms of Interacting Partners?
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