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CALCA and RAMP1
Data Source:
HPRD
(in vivo)
CALCA
RAMP1
Description
calcitonin related polypeptide alpha
receptor activity modifying protein 1
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Neuronal Cell Body
Terminal Bouton
Extracellular Space
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Surface
Receptor Complex
Amylin Receptor Complex 1
CGRP Receptor Complex
Molecular Function
Hormone Activity
Protein Binding
Calcitonin Receptor Binding
Identical Protein Binding
Calcitonin Gene-related Peptide Receptor Activity
Protein Binding
Coreceptor Activity
Amylin Receptor Activity
Calcitonin Gene-related Peptide Binding
Biological Process
Artery Vasodilation Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure
Monocyte Chemotaxis
Inflammatory Response
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Activation Of Adenylate Cyclase Activity
Positive Regulation Of Cytosolic Calcium Ion Concentration
Neuropeptide Signaling Pathway
Embryo Implantation
Aging
Feeding Behavior
Regulation Of Heart Contraction
Response To Heat
Negative Regulation Of Ossification
Activation Of Protein Kinase Activity
Cellular Protein Metabolic Process
Negative Regulation Of Bone Resorption
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Smooth Muscle Contraction
Response To Pain
Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain
Regulation Of Cytosolic Calcium Ion Concentration
Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Cellular Response To Tumor Necrosis Factor
Cellular Response To Nerve Growth Factor Stimulus
Angiogenesis
Calcium Ion Transport
Intracellular Protein Transport
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Regulation Of G Protein-coupled Receptor Signaling Pathway
Protein Transport
Receptor Internalization
Positive Regulation Of Protein Binding
Cellular Response To Hormone Stimulus
Positive Regulation Of Protein Glycosylation
Protein Localization To Plasma Membrane
Amylin Receptor Signaling Pathway
Calcitonin Gene-related Peptide Receptor Signaling Pathway
Pathways
G alpha (s) signalling events
Calcitonin-like ligand receptors
ADORA2B mediated anti-inflammatory cytokines production
Amyloid fiber formation
G alpha (s) signalling events
Calcitonin-like ligand receptors
ADORA2B mediated anti-inflammatory cytokines production
G alpha (s) signalling events
Calcitonin-like ligand receptors
ADORA2B mediated anti-inflammatory cytokines production
Drugs
Olcegepant
Telcagepant
Eptinezumab
Fremanezumab
Galcanezumab
Pramlintide
Diseases
GWAS
Diverticular disease (
30177863
)
Vitamin D levels (
25208829
)
Obesity-related traits (
23251661
)
Resting metabolic rate (
28476931
)
Interacting Genes
8 interacting genes:
ANKRD11
BBS1
BBS4
CALCRL
ECE1
NRDC
RAMP1
RAMP2
9 interacting genes:
CALCA
CALCR
CALCRL
IAPP
MAL
MS4A13
NKG7
SLC31A2
VIPR1
Entrez ID
796
10267
HPRD ID
00238
05515
Ensembl ID
ENSG00000110680
ENSG00000132329
Uniprot IDs
P01258
P06881
E9PC20
O60894
PDB IDs
1LS7
2JXZ
6E3Y
2YX8
3N7P
3N7R
3N7S
4RWG
5V6Y
6D1U
6E3Y
6UMG
6ZHO
6ZIS
Enriched GO Terms of Interacting Partners
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