SAP130 and GPS1

		SAP130	GPS1
Description		Sin3A associated protein 130	G protein pathway suppressor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Speck Sin3-type Complex	Nucleoplasm Cytosol COP9 Signalosome
	Molecular Function		GTPase Inhibitor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Inactivation Of MAPK Activity Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition Transcription-coupled Nucleotide-excision Repair JNK Cascade Negative Regulation Of GTPase Activity Post-translational Protein Modification
Pathways		HATs acetylate histones NoRC negatively regulates rRNA expression	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs
Diseases
GWAS		Anti-saccade response ( 29064472) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		6 interacting genes: ARID4B CCR9 CUL2 GPS1 MYC SMAD3	29 interacting genes: CNOT2 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 COPS9 CUL1 CUL2 CUL3 CUL4A CUL5 DDB1 ELOB IP6K1 ITPK1 RBX1 SAP130 SENP8 SKP1 SKP2 TBC1D17 TP53 TRIM55 TRIM63 VHL
Entrez ID		79595	2873
HPRD ID		18015	15991
Ensembl ID		ENSG00000136715	ENSG00000169727
Uniprot IDs		A0A2R8YDB8 H7BXF5 Q96DP1 Q9H0E3	A0A096LP07 A0A096LPJ3 C9JFE4 Q13098
PDB IDs			4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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