UBE2T and MGRN1

Data Source:
BioGRID (two hybrid)

		UBE2T	MGRN1
Description		ubiquitin conjugating enzyme E2 T	mahogunin ring finger 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleus Cytoplasm Early Endosome Endoplasmic Reticulum Cytosol Plasma Membrane Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination DNA Repair Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Protein Ubiquitination Protein K29-linked Ubiquitination Interstrand Cross-link Repair Protein K27-linked Ubiquitination Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination	Protein Monoubiquitination Endosome To Lysosome Transport Protein Ubiquitination Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Smoothened Signaling Pathway
Pathways		Fanconi Anemia Pathway Synthesis of active ubiquitin: roles of E1 and E2 enzymes	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Breast cancer ( 23535733) Celiac disease ( 23936387)	HDL cholesterol levels ( 32203549) Hemoglobin ( 32888494) Milk allergy (maternal genetic effects) ( 29489655) Triglyceride levels ( 32154731)
Interacting Genes		22 interacting genes: AMFR ARIH2 BRCA1 CDK2 CHEK1 FANCD2 FANCL LNX2 MARCHF5 MGRN1 PCGF2 PRKCG PRKN RNF128 RNF144B RNF31 RNF4 ROCK1 RPS6KA1 TRIM27 UBA1 UBA6	13 interacting genes: AMFR TRIM74 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2G2 UBE2I UBE2J2 UBE2T UBE2W
Entrez ID		29089	23295
HPRD ID		13704	07397
Ensembl ID		ENSG00000077152	ENSG00000102858
Uniprot IDs		A0A024R9A9 Q9NPD8	O60291
PDB IDs		1YH2 4CCG 5NGZ 5OJJ 6R75
Enriched GO Terms of Interacting Partners?
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