FA2H and FAM209A

Data Source:
BioGRID (two hybrid)

		FA2H	FAM209A
Description		fatty acid 2-hydroxylase	family with sequence similarity 209 member A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Nucleus Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Iron Ion Binding Protein Binding Heme Binding Fatty Acid Alpha-hydroxylase Activity	Molecular_function Protein Binding
	Biological Process	Sebaceous Gland Cell Differentiation Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Glucosylceramide Biosynthetic Process Galactosylceramide Biosynthetic Process Sphingolipid Biosynthetic Process Lipid Modification Central Nervous System Myelin Maintenance Peripheral Nervous System Myelin Maintenance Regulation Of Cell Population Proliferation Regulation Of Hair Cycle Plasma Membrane Raft Organization Ceramide Biosynthetic Process Establishment Of Skin Barrier	Biological_process
Pathways		Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		General cognitive ability ( 25383866) Pancreatic cancer ( 25086665) White matter lesion progression (adjusted for white matter lesion burden at baseline) ( 26451028)	Heschl's gyrus morphology ( 25130324)
Interacting Genes		31 interacting genes: AQP6 ARMC12 ASGR2 CD79A CREB3 CREB3L1 DLG2 EBP ELOVL4 ERGIC3 ERLIN1 FAM209A FCER1G GPR152 GPR37 GPX8 LMNA MARCHF8 MSR1 PEX12 PGRMC2 RIC3 SGPL1 SLC10A1 SLC10A6 SYT2 TLCD4 TMEM14B TMEM41A TMX2 UBQLN4	231 interacting genes: - ADGRE2 ADIPOQ AGTRAP AIG1 ALG8 ANKRD46 APMAP APOC3 APOD APOL2 AQP1 AQP2 AQP3 ARV1 ASGR1 ATP13A1 B4GALNT2 BDNF BET1 BIK BMP10 BNIP2 BNIP3 BTN2A2 C11orf24 C14orf180 C1GALT1 C2 C3orf52 C4orf3 CANT1 CCL4L2 CD53 CD59 CD81 CDIPT CDS1 CDS2 CLCA4 CLDN19 CLDN2 CLDN4 CLDND2 CLEC4G CLN6 CMTM7 CNIH1 CNPY3 COL4A5 COL8A2 COMT CTRL CTSA CTXN3 CXCL16 CYB561D2 CYB5B CYBC1 DEFB121 DEFB128 DNAJC30 DOLK EBP EMC6 EMD ENTPD3 EOGT ERG28 ERMP1 FA2H FAM20B FAM3C FATE1 FCER1G FDFT1 FIS1 FXYD3 GAST GET3 GHITM GIMAP1 GJB2 GKN1 GKN2 GOSR2 GPR108 GPR151 GPR37L1 GYPA HACD2 HHATL HMOX1 HMOX2 HTATIP2 IGFBP5 INSIG2 JAGN1 KIR2DL3 LHFPL5 LPAR3 LRP10 MAL MARCHF2 MFF MGLL MIP MMD MMD2 MS4A1 MS4A13 MYADM MYADML2 NAPB NAT8 NCR3 NINJ2 NRM NXPE3 OLFM4 ORMDL3 OTOR PAQR7 PEDS1-UBE2V1 PGAP2 PGLYRP3 PLN PLP1 PLP2 PLPP4 PLPP6 PMP22 PNLIPRP1 PRB1 PTCH1 RHAG RPRM RTP2 RUSF1 S100A2 SCARF1 SCGB1D1 SCRG1 SEC22A SEC22B SEC61G SELENOK SEMA6C SERP1 SFTPC SLC13A3 SLC1A1 SLC30A8 SLC35A1 SLC35A4 SLC35B4 SLC35E3 SLC35G2 SLC38A7 SLC52A2 SLC7A14 SMCO4 SMIM1 SNORC STATH STX1B STX3 STX5 STX8 SYNGR1 SYT15 TECR TEX264 TFRC THBD THSD7B TM6SF2 TMBIM6 TMEM100 TMEM107 TMEM11 TMEM120A TMEM128 TMEM140 TMEM141 TMEM14B TMEM14C TMEM203 TMEM208 TMEM218 TMEM222 TMEM229B TMEM236 TMEM243 TMEM254 TMEM42 TMEM43 TMEM47 TMEM50B TMEM60 TMEM65 TMEM72 TMEM79 TMEM86A TMEM86B TMEM97 TMPRSS4 TMUB2 TNF TNFRSF10C TNMD TRAF3IP3 TRAM1L1 TSPAN2 TSPAN33 TSPAN7 TSPO TWSG1 UBE2J1 UBIAD1 UNC50 UPK1B VAMP3 VAMP4 VAMP5 VKORC1 VMP1 WFDC2 WFS1 YIPF6 ZFPL1
Entrez ID		79152	200232
HPRD ID		16873	18536
Ensembl ID		ENSG00000103089	ENSG00000124103
Uniprot IDs		Q7L5A8	Q5JX71
PDB IDs
Enriched GO Terms of Interacting Partners?
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