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FA2H and TMEM41A
Data Source:
BioGRID
(two hybrid)
FA2H
TMEM41A
Description
fatty acid 2-hydroxylase
transmembrane protein 41A
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Integral Component Of Membrane
Molecular Function
Iron Ion Binding
Protein Binding
Heme Binding
Fatty Acid Alpha-hydroxylase Activity
Protein Binding
Biological Process
Sebaceous Gland Cell Differentiation
Fatty Acid Metabolic Process
Fatty Acid Biosynthetic Process
Glucosylceramide Biosynthetic Process
Galactosylceramide Biosynthetic Process
Sphingolipid Biosynthetic Process
Lipid Modification
Central Nervous System Myelin Maintenance
Peripheral Nervous System Myelin Maintenance
Regulation Of Cell Population Proliferation
Regulation Of Hair Cycle
Plasma Membrane Raft Organization
Ceramide Biosynthetic Process
Establishment Of Skin Barrier
Pathways
Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS
General cognitive ability (
25383866
)
Pancreatic cancer (
25086665
)
White matter lesion progression (adjusted for white matter lesion burden at baseline) (
26451028
)
Interacting Genes
31 interacting genes:
AQP6
ARMC12
ASGR2
CD79A
CREB3
CREB3L1
DLG2
EBP
ELOVL4
ERGIC3
ERLIN1
FAM209A
FCER1G
GPR152
GPR37
GPX8
LMNA
MARCHF8
MSR1
PEX12
PGRMC2
RIC3
SGPL1
SLC10A1
SLC10A6
SYT2
TLCD4
TMEM14B
TMEM41A
TMX2
UBQLN4
9 interacting genes:
CYB5B
FA2H
FXYD6-FXYD2
KASH5
LMNA
LPAR3
NOTCH2NLA
PTPN1
STX1A
Entrez ID
79152
90407
HPRD ID
16873
15539
Ensembl ID
ENSG00000103089
ENSG00000163900
Uniprot IDs
Q7L5A8
Q96HV5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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