DHX58 and DHX30

Data Source:
BioGRID (pull down)

		DHX58	DHX30
Description		DExH-box helicase 58	DExH-box helicase 30
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GO Annotations	Cellular Component	Cytoplasm	Intracellular Anatomical Structure Cytoplasm Mitochondrion Cytosol Ribonucleoprotein Granule Mitochondrial Nucleoid
	Molecular Function	DNA Binding RNA Helicase Activity Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding ATP Binding Zinc Ion Binding	Chromatin Binding RNA Binding RNA Helicase Activity Double-stranded RNA Binding Protein Binding ATP Binding
	Biological Process	Response To Virus Response To Bacterium Viral Process Negative Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Negative Regulation Of MDA-5 Signaling Pathway Negative Regulation Of RIG-I Signaling Pathway Innate Immune Response Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Defense Response To Virus Positive Regulation Of MDA-5 Signaling Pathway Positive Regulation Of RIG-I Signaling Pathway	Central Nervous System Development Mitochondrial Large Ribosomal Subunit Assembly
Pathways		DDX58/IFIH1-mediated induction of interferon-alpha/beta
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Fasting plasma glucose ( 31932636) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		9 interacting genes: AGO2 AP2B1 APP DHX30 DICER1 EIF2AK2 EIF6 NKRF STAU2	17 interacting genes: CDK9 DHX58 DUX4 HDAC1 HDAC3 HNRNPD MYBBP1A NCOR1 NEDD4 NR2E3 OAS3 RBBP4 RBBP7 RBL1 SIN3A SKIL TBL3
Entrez ID		79132	22907
HPRD ID		13115	13142
Ensembl ID		ENSG00000108771	ENSG00000132153
Uniprot IDs		A0A024R1Y5 Q96C10	H7BXY3 Q7L2E3
PDB IDs		2RQA 2W4R 3EQT	2DB2
Enriched GO Terms of Interacting Partners?
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