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DHX58 and NKRF
Data Source:
BioGRID
(pull down)
DHX58
NKRF
Description
DExH-box helicase 58
NFKB repressing factor
Image
GO Annotations
Cellular Component
Cytoplasm
Nucleus
Nucleoplasm
Nucleolus
Molecular Function
DNA Binding
RNA Helicase Activity
Double-stranded RNA Binding
Single-stranded RNA Binding
Protein Binding
ATP Binding
Zinc Ion Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
RNA Binding
Protein Binding
Biological Process
Response To Virus
Response To Bacterium
Viral Process
Negative Regulation Of Type I Interferon Production
Positive Regulation Of Type I Interferon Production
Positive Regulation Of Interferon-beta Production
Negative Regulation Of MDA-5 Signaling Pathway
Negative Regulation Of RIG-I Signaling Pathway
Innate Immune Response
Regulation Of Innate Immune Response
Negative Regulation Of Innate Immune Response
Defense Response To Virus
Positive Regulation Of MDA-5 Signaling Pathway
Positive Regulation Of RIG-I Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
DDX58/IFIH1-mediated induction of interferon-alpha/beta
Drugs
Diseases
GWAS
Coronary artery disease (
29212778
)
Fasting plasma glucose (
31932636
)
Mean spheric corpuscular volume (
32888494
)
Interacting Genes
9 interacting genes:
AGO2
AP2B1
APP
DHX30
DICER1
EIF2AK2
EIF6
NKRF
STAU2
12 interacting genes:
ADARB1
DHX15
DHX58
HMOX2
KIFC1
NFKB1
NFKB2
PRKRA
REL
RELA
STAU1
ZNF346
Entrez ID
79132
55922
HPRD ID
13115
02341
Ensembl ID
ENSG00000108771
ENSG00000186416
Uniprot IDs
A0A024R1Y5
Q96C10
A3F769
O15226
PDB IDs
2RQA
2W4R
3EQT
6SH6
6SH7
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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