DHX30 and RBL1

Data Source:
HPRD (in vivo)

		DHX30	RBL1
Description		DExH-box helicase 30	RB transcriptional corepressor like 1
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GO Annotations	Cellular Component	Intracellular Anatomical Structure Cytoplasm Mitochondrion Cytosol Ribonucleoprotein Granule Mitochondrial Nucleoid	Chromatin Nucleoplasm Transcription Regulator Complex
	Molecular Function	Chromatin Binding RNA Binding RNA Helicase Activity Double-stranded RNA Binding Protein Binding ATP Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Activating Transcription Factor Binding Protein Binding Transcription Factor Binding Promoter-specific Chromatin Binding
	Biological Process	Central Nervous System Development Mitochondrial Large Ribosomal Subunit Assembly	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Cell Cycle Negative Regulation Of Gene Expression Viral Process Cell Differentiation Regulation Of Lipid Kinase Activity Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Division Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cellular Senescence
Pathways			Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest G1/S-Specific Transcription Cyclin D associated events in G1
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Diseases
GWAS			Height ( 25429064) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 28957414)
Interacting Genes		17 interacting genes: CDK9 DHX58 DUX4 HDAC1 HDAC3 HNRNPD MYBBP1A NCOR1 NEDD4 NR2E3 OAS3 RBBP4 RBBP7 RBL1 SIN3A SKIL TBL3	54 interacting genes: AOX1 BEGAIN BRCA1 BRF1 CCNA1 CCNA2 CCND1 CCNE1 CDK2 CDK4 CDK6 CEBPA CREG1 DGKZ DHX30 DYRK1A E2F1 E2F4 E2F5 EPHA2 FN1 GOLGA2 HDAC1 ID2 IRF3 KDM5A KMT5C LAMB2 MAPK6 MCM7 MYBL2 MYC NR2E3 NR4A1 NUCB1 PHB PLSCR1 PPP2R3A RBBP8 RBBP9 RINT1 SMAD2 SMAD3 SMAD4 SMARCA4 SNRPD3 SNW1 SP1 SUV39H1 TAF1 TOP1 TP53BP1 TSC22D2 USP4
Entrez ID		22907	5933
HPRD ID		13142	00312
Ensembl ID		ENSG00000132153	ENSG00000080839
Uniprot IDs		H7BXY3 Q7L2E3	P28749
PDB IDs		2DB2	1H28 4YOO 4YOS 4YOZ 5TUV
Enriched GO Terms of Interacting Partners?
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