ZSCAN26 and LSM7

Data Source:
BioGRID (two hybrid)

		ZSCAN26	LSM7
Description		zinc finger and SCAN domain containing 26	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleus Nucleoplasm U6 SnRNP U12-type Spliceosomal Complex Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex Lsm2-8 Complex Lsm1-7-Pat1 Complex Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	RNA Binding Protein Binding U6 SnRNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II	MRNA Splicing, Via Spliceosome Exonucleolytic Catabolism Of Deadenylated MRNA
Pathways			mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Refractive error ( 32231278)	Parkinson's disease ( 28892059)
Interacting Genes		16 interacting genes: CCDC136 CCNDBP1 CDR2L FSD2 GOLGA6L9 KRTAP10-1 KRTAP10-3 KRTAP10-4 KRTAP10-5 KRTAP10-7 KRTAP10-9 KRTAP4-12 LSM7 MTUS2 PDE4DIP TRIM41	25 interacting genes: DDIT4L EPHA2 EXOSC6 EXOSC8 LDB1 LSM1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM8 MYH13 NPY1R PFKM RAB29 RASSF5 SART3 SMN1 SNRPD3 SNRPF SYT17 TACC1 TCL1B ZSCAN26
Entrez ID		7741	51690
HPRD ID		15746	06287
Ensembl ID		ENSG00000197062	ENSG00000130332
Uniprot IDs		A0A024RCN4 A0A087X2F1 B3KTR1 B4DMT1 B4DVH3 Q16670	Q9UK45
PDB IDs			3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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