LSM7 and LSM5

Data Source:
HPRD (in vivo, in vitro)

		LSM7	LSM5
Description		LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated	LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U6 SnRNP U12-type Spliceosomal Complex Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex Lsm2-8 Complex Lsm1-7-Pat1 Complex Ribonucleoprotein Complex	Nucleus Nucleoplasm U6 SnRNP Cytoplasm Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Lsm2-8 Complex Lsm1-7-Pat1 Complex
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding	RNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	MRNA Splicing, Via Spliceosome Exonucleolytic Catabolism Of Deadenylated MRNA	MRNA Splicing, Via Spliceosome MRNA Processing MRNA Catabolic Process Response To Bacterium Exonucleolytic Catabolism Of Deadenylated MRNA
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway	mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Parkinson's disease ( 28892059)	Body mass index ( 26426971) Extremely high intelligence ( 29520040) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Morning person ( 30696823) Palmitic acid (16:0) levels ( 23362303) Smooth-surface caries ( 24556642)
Interacting Genes		25 interacting genes: DDIT4L EPHA2 EXOSC6 EXOSC8 LDB1 LSM1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM8 MYH13 NPY1R PFKM RAB29 RASSF5 SART3 SMN1 SNRPD3 SNRPF SYT17 TACC1 TCL1B ZSCAN26	16 interacting genes: DDIT4L EXOSC5 HNRNPD LSM1 LSM2 LSM3 LSM6 LSM7 LSM8 PLK3 SMN1 SNRPE SNRPF TBPL1 TCL1B TEX43
Entrez ID		51690	23658
HPRD ID		06287	06285
Ensembl ID		ENSG00000130332	ENSG00000106355
Uniprot IDs		Q9UK45	A0A090N8Y5 Q9Y4Y9
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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