LSM7 and TCL1B

Data Source:
BioGRID (two hybrid)

		LSM7	TCL1B
Description		LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated	TCL1 family AKT coactivator B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U6 SnRNP U12-type Spliceosomal Complex Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex Lsm2-8 Complex Lsm1-7-Pat1 Complex Ribonucleoprotein Complex	Protein-containing Complex
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding	Protein Binding Protein Kinase Binding Protein Serine/threonine Kinase Activator Activity
	Biological Process	MRNA Splicing, Via Spliceosome Exonucleolytic Catabolism Of Deadenylated MRNA	Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Serine/threonine Kinase Activity
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Parkinson's disease ( 28892059)	Refractive error ( 32231278)
Interacting Genes		25 interacting genes: DDIT4L EPHA2 EXOSC6 EXOSC8 LDB1 LSM1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM8 MYH13 NPY1R PFKM RAB29 RASSF5 SART3 SMN1 SNRPD3 SNRPF SYT17 TACC1 TCL1B ZSCAN26	17 interacting genes: AKT1 AKT2 APP BAG4 EFCAB2 GLRX3 LSM1 LSM5 LSM7 MARK1 MEIS3 MKRN3 PLEKHA3 PNMA1 SNRPG TNPO2 ZNF330
Entrez ID		51690	9623
HPRD ID		06287	04795
Ensembl ID		ENSG00000130332	ENSG00000213231
Uniprot IDs		Q9UK45	A0A024R6P4 O95988
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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