CACNA1B and CACNB3

Data Source:
HPRD (in vitro)

		CACNA1B	CACNB3
Description		calcium voltage-gated channel subunit alpha1 B	calcium voltage-gated channel auxiliary subunit beta 3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Calcium Channel Complex Synapse	Cytosol Plasma Membrane Voltage-gated Calcium Channel Complex Membrane Apical Plasma Membrane Synapse L-type Voltage-gated Calcium Channel Complex
	Molecular Function	Amyloid-beta Binding Voltage-gated Calcium Channel Activity Calcium Ion Binding Protein Binding ATP Binding Protein C-terminus Binding High Voltage-gated Calcium Channel Activity	Voltage-gated Calcium Channel Activity Calcium Channel Regulator Activity Protein Binding High Voltage-gated Calcium Channel Activity Protein Kinase Binding
	Biological Process	Calcium Ion Transport Chemical Synaptic Transmission Regulation Of Ion Transmembrane Transport Modulation Of Chemical Synaptic Transmission Membrane Depolarization Calcium Ion Import Calcium Ion Transmembrane Transport Response To Amyloid-beta	Calcium Ion Transport Chemical Synaptic Transmission Neuromuscular Junction Development T Cell Receptor Signaling Pathway Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Membrane Depolarization Calcium Ion Transport Into Cytosol Cardiac Conduction Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Protein Localization To Plasma Membrane Positive Regulation Of Protein Targeting To Membrane Cellular Response To Oxygen-glucose Deprivation Regulation Of Membrane Repolarization During Action Potential Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Membrane Hyperpolarization Negative Regulation Of Detection Of Mechanical Stimulus Involved In Sensory Perception Of Touch Positive Regulation Of Excitatory Postsynaptic Potential
Pathways		Presynaptic depolarization and calcium channel opening	Presynaptic depolarization and calcium channel opening Adrenaline,noradrenaline inhibits insulin secretion NCAM1 interactions Regulation of insulin secretion Regulation of insulin secretion
Drugs		Ergocalciferol Enflurane Amlodipine Amlodipine Spironolactone Verapamil Gabapentin Levetiracetam Seletracetam Contulakin-G Ziconotide Agmatine Benidipine Cilnidipine Butamben Bioallethrin	Ergocalciferol Enflurane Ranolazine Phenytoin Topiramate Nimodipine Spironolactone Magnesium sulfate Levomenthol Miconazole Amiodarone Mibefradil Dronedarone Trimebutine Benidipine Cilnidipine Lacidipine Manidipine Butamben Bioallethrin Bioallethrin Fish oil
Diseases
GWAS		Asparaginase hypersensitivity in acute lymphoblastic leukemia ( 25987655) Bipolar disorder ( 31043756) Body mass index ( 28552196) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Parkinson's disease ( 32201043) Weight ( 28552196)
Interacting Genes		9 interacting genes: APBA1 CACNB3 GNAO1 GNB1 PDLIM5 PPM1A RGS12 RIMS1 RXRB	12 interacting genes: C20orf85 CACNA1B CACNA1C CEP76 CIAPIN1 CTBP2 FASLG GEM MEOX1 MTUS2 SKIV2L SYT1
Entrez ID		774	784
HPRD ID		03005	11879
Ensembl ID		ENSG00000148408	ENSG00000167535
Uniprot IDs		Q00975	P54284
PDB IDs		2LCM
Enriched GO Terms of Interacting Partners?
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