LRCH4 and CA8

		LRCH4	CA8
Description		leucine rich repeats and calponin homology domain containing 4	carbonic anhydrase 8
Image		No pdb structure
GO Annotations	Cellular Component	PML Body	Cytoplasm
	Molecular Function	Protein Binding	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Hydro-lyase Activity
	Biological Process	Nervous System Development	One-carbon Metabolic Process Phosphatidylinositol-mediated Signaling
Pathways
Drugs			Zonisamide
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Macular thickness ( 30535121) Subcortical volume (MOSTest) ( 32665545)	Adult body size ( 32376654) Blood protein levels ( 30072576) Cardiac hypertrophy ( 21348951) Free thyroxine concentration ( 30367059) Height ( 31562340) Hemoglobin ( 32888494) Myopia ( 27182965) Obesity-related traits ( 23251661) Parkinson's disease ( 27182965) Red blood cell count ( 32888494) Refractive error ( 32231278) Response to amphetamines ( 22952603) Schizophrenia ( 28991256 25056061 29483656 30285260) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		16 interacting genes: CA8 CYB5R3 ELOVL7 HSD17B11 KASH5 KRT40 KRTAP10-7 KRTAP10-8 MDFI NOTCH2NLA RBBP6 RETREG3 RNASEK RTN4 SIN3A SPOP	14 interacting genes: CRX GGA2 HSD17B14 INTS7 ITPR1 KLHL8 LMNB2 LNX1 LRCH4 MAGED1 RAB34 SPDL1 STAT3 TBX3
Entrez ID		4034	767
HPRD ID		10062	00266
Ensembl ID		ENSG00000077454	ENSG00000178538
Uniprot IDs		O75427	P35219
PDB IDs			2W2J
Enriched GO Terms of Interacting Partners?
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