ZNF23 and PCBD1

Data Source:
BioGRID (two hybrid)

		ZNF23	PCBD1
Description		zinc finger protein 23	pterin-4 alpha-carbinolamine dehydratase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Transcription Coactivator Activity Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	L-phenylalanine Catabolic Process Tetrahydrobiopterin Biosynthetic Process Regulation Of Protein Binding Positive Regulation Of Transcription, DNA-templated
Pathways		Generic Transcription Pathway	Phenylalanine metabolism
Drugs			L-erythro-7,8-dihydrobiopterin
Diseases			Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
GWAS		General risk tolerance (MTAG) ( 30643258) Waist circumference adjusted for body mass index ( 28552196)	Blood protein levels ( 30072576) Chronotype ( 30696823) Immature fraction of reticulocytes ( 27863252) Microalbuminuria ( 26631737) Obesity-related traits ( 23251661)
Interacting Genes		22 interacting genes: APP ATPAF2 DYSF ELOA2 FHL2 FHL5 GLRX3 GMCL1 KRTAP10-3 KRTAP10-8 MCRS1 MDFI MEOX2 MOBP MTUS2 NME7 PCBD1 SPRY1 TRAF1 TSGA10 ZBTB9 ZNF330	54 interacting genes: ACIN1 APP BRD7 CACNA1C CALCOCO1 CDK5RAP2 CEBPZ DENND4A DIP2C DVL2 DYRK1B EHMT1 FXR2 GORASP2 GTF3C3 HES4 HNF1A HNF1B HNF4A KANK2 KLF13 LNX1 MIS18BP1 NFKB1 NIF3L1 NTAQ1 NUDT18 PAH PAPOLG PCBD2 PICK1 POLR3A PSMA1 RBL2 RPS24 SAP30 SCMH1 SDCBP SMARCD1 SOWAHC SUPT5H TFF3 TIMELESS TRIM5 WWP1 ZBTB25 ZNF195 ZNF202 ZNF23 ZNF263 ZNF451 ZNF567 ZNF688 ZNF714
Entrez ID		7571	5092
HPRD ID		01915	00523
Ensembl ID		ENSG00000167377	ENSG00000166228
Uniprot IDs		B3KR55 B4DLS2 P17027	P61457
PDB IDs
Enriched GO Terms of Interacting Partners?
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