XPA and ERCC4

XPA

ERCC4

Description XPA, DNA damage recognition and repair factor ERCC excision repair 4, endonuclease catalytic subunit
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Hypothyroidism ( 27182965)
  • Obesity-related traits ( 23251661)
  • Serum thyroid-stimulating hormone levels ( 24852370)
  • Thyroid cancer (Papillary, radiation-related) ( 20350937)
Interacting Genes 51 interacting genes: ARID3A ATM ATR AURKA BMPR1A BUB1 DDB1 DDB2 DLC1 DVL3 ERCC1 ERCC4 ERCC6 FBXW7 GPN1 GTF2E2 GTF2H1 HERC2 MEOX2 MLH1 MLH3 MSH2 MSH3 MUTYH NDEL1 NRAS PCNA PDGFRL PICK1 PMS2 POLR1C PRDM16 PRKDC PSMB1 RASSF1 RB1 RHOU RPA1 RPA2 RPA4 SKIL SMAD2 SNPH SRC STK11 TBC1D7 TRIM27 VPS26C XAB2 XPC ZNF655 13 interacting genes: ERCC1 FANCG GTF2H1 KIF11 RAD52 RPA1 RPA2 SLX1A SLX4 SPTAN1 SUMO2 TACC1 XPA
Entrez ID 7507 2072
HPRD ID 02045 00594
Ensembl ID ENSG00000136936 ENSG00000175595
Uniprot IDs P23025 A0A1W1GSK9 B4DXD8 Q92889
PDB IDs 1D4U 1XPA 2JNW 6J44 6LAE 6RO4 1Z00 2A1J 2AQ0 2KN7 2MUT 6SXA 6SXB
Enriched GO Terms of Interacting Partners?
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