UBE2G1 and CUL9

Data Source:
BioGRID (pull down)

		UBE2G1	CUL9
Description		ubiquitin conjugating enzyme E2 G1	cullin 9
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GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Cytosol Cullin-RING Ubiquitin Ligase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity	Protein Binding ATP Binding Transferase Activity Ubiquitin Protein Ligase Binding Metal Ion Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Protein Catabolic Process Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination	Microtubule Cytoskeleton Organization Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Nuclear Division Protein Ubiquitination Post-translational Protein Modification
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation	Neddylation
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Plasma trimethylamine N-oxide levels ( 28439531) Refractive error ( 32231278) Small cell lung carcinoma ( 28604730)	Adult hearing difficulty ( 31564434) General risk tolerance (MTAG) ( 30643258) Obesity-related traits ( 23251661) Tea consumption ( 31046077)
Interacting Genes		19 interacting genes: AMFR APP CBL CUL9 DIO2 FBXL2 HUWE1 ITCH MAP3K1 MARCHF6 PRKN RBCK1 RBX1 RC3H1 SMURF1 SYVN1 UBA1 UBE2E1 UBE3A	8 interacting genes: CYCS MTDH PLXNB3 TP53 UBE2E2 UBE2G1 UBE2G2 UBE2L3
Entrez ID		7326	23113
HPRD ID		03340	06317
Ensembl ID		ENSG00000132388	ENSG00000112659
Uniprot IDs		P62253	Q8IWT3
PDB IDs		2AWF 6D68	2JUF
Enriched GO Terms of Interacting Partners?
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