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UBE2G1 and SYVN1
Data Source:
BioGRID
(enzymatic study)
UBE2G1
SYVN1
Description
ubiquitin conjugating enzyme E2 G1
synoviolin 1
Image
GO Annotations
Cellular Component
Cytosol
Extracellular Exosome
Hrd1p Ubiquitin Ligase Complex
Hrd1p Ubiquitin Ligase ERAD-L Complex
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Smooth Endoplasmic Reticulum
Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Derlin-1 Retrotranslocation Complex
Endoplasmic Reticulum Quality Control Compartment
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Conjugating Enzyme Activity
Protein Binding
Metal Ion Binding
Unfolded Protein Binding
Chaperone Binding
ATPase Binding
Ubiquitin Protein Ligase Activity
Ubiquitin-specific Protease Binding
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Catabolic Process
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Immature B Cell Differentiation
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Ubiquitin-dependent ERAD Pathway
Retrograde Protein Transport, ER To Cytosol
IRE1-mediated Unfolded Protein Response
ERAD Pathway
Protein Stabilization
Protein K48-linked Ubiquitination
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Endoplasmic Reticulum Mannose Trimming
Pathways
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation
XBP1(S) activates chaperone genes
Hedgehog ligand biogenesis
Hh mutants are degraded by ERAD
ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Plasma trimethylamine N-oxide levels (
28439531
)
Refractive error (
32231278
)
Small cell lung carcinoma (
28604730
)
Blood protein levels (
28240269
)
Crohn's disease (
32581322
)
Interacting Genes
19 interacting genes:
AMFR
APP
CBL
CUL9
DIO2
FBXL2
HUWE1
ITCH
MAP3K1
MARCHF6
PRKN
RBCK1
RBX1
RC3H1
SMURF1
SYVN1
UBA1
UBE2E1
UBE3A
13 interacting genes:
APP
ATN1
CLU
ERN1
GPR37
TP53
UBE2D2
UBE2D3
UBE2G1
UBE2U
UBE2Z
USP15
USP7
Entrez ID
7326
84447
HPRD ID
03340
07618
Ensembl ID
ENSG00000132388
ENSG00000162298
Uniprot IDs
P62253
Q86TM6
PDB IDs
2AWF
6D68
6A3Z
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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