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C8A and GPR152
Data Source:
BioGRID
(two hybrid)
C8A
GPR152
Description
complement C8 alpha chain
G protein-coupled receptor 152
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Membrane Attack Complex
Extracellular Space
Membrane
Extracellular Exosome
Blood Microparticle
Plasma Membrane
Integral Component Of Membrane
Molecular Function
Complement Binding
Protein Binding
Protein-containing Complex Binding
G Protein-coupled Receptor Activity
Protein Binding
Identical Protein Binding
Biological Process
Immune Response
Complement Activation
Complement Activation, Alternative Pathway
Complement Activation, Classical Pathway
Cytolysis
Regulation Of Complement Activation
G Protein-coupled Receptor Signaling Pathway
Pathways
Terminal pathway of complement
Regulation of Complement cascade
Drugs
Zinc
Zinc acetate
Diseases
Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
GWAS
Blood protein levels (
28240269
)
Non-response to citalopram or escitalopram and depression (
27622933
)
Refractive error (
32231278
)
Interacting Genes
9 interacting genes:
C8B
C8G
C9
CD59
GOLT1A
GPR152
MMGT1
SLC10A1
SLC7A1
194 interacting genes:
-
ABCG4
ABHD16A
ACSF2
ADIPOQ
AGTRAP
AIG1
ANKRD46
APOL3
AQP10
AQP3
AQP6
ARL6IP1
ARV1
ATP6V0C
B3GNT7
BDNF
BET1
BMP10
BNIP2
BNIP3
C14orf180
C1QL4
C8A
CCDC167
CCL4
CCL4L2
CD53
CD72
CD81
CDIPT
CDS2
CGRRF1
CLDND2
CLEC17A
CLEC1A
CLN5
CNIH1
COL8A2
COMT
CRISP3
CSGALNACT2
CTXN3
CYB561
CYB561A3
CYB5B
CYB5R3
CYBC1
DEFB108B
DGAT2L6
EBP
EDDM3B
EFNA5
EMD
ERG28
FA2H
FAM20B
FAXDC2
FDFT1
FUNDC2
FXYD3
FXYD6-FXYD2
GAST
GJB2
GOLT1A
GOLT1B
GOSR2
GPR151
GPR37L1
HHATL
HMOX1
HMOX2
IFNA8
IGF2
IGFBP5
IL1RL1
INS-IGF2
INSIG2
JAGN1
KCNA1
KCNN4
LAMB1
LAT
LEPROTL1
LHFPL2
LHFPL5
LTC4S
MAL
MAL2
MFF
MFSD5
MFSD6
MGLL
MGST3
MMD
MOSPD3
MS4A13
MYADML2
NAT8
NDUFB11
NEU1
NINJ2
NIPAL4
ORMDL1
ORMDL3
PEDS1-UBE2V1
PEX16
PGAP2
PIGF
PIN1
PLN
PNLIPRP1
PRAF2
PROM2
PTPRN
RABAC1
RBFA
REEP6
ROBO2
RTN3
RTP2
SACM1L
SCAMP4
SCD
SEC22B
SERF1A
SERF1B
SERP2
SFT2D2
SFTPC
SLC10A1
SLC13A4
SLC29A2
SLC30A3
SLC35A4
SLC35B1
SLC35B4
SLC35C2
SLC35F6
SLC38A1
SLC38A7
SLC39A2
SLC41A1
SLC66A1
SLC66A2
SLC7A1
SMCO4
STATH
STX1B
STX3
STX4
STX5
STX8
SYT15
TAP1
TEX264
TFRC
THSD7B
TIMMDC1
TM4SF19
TMEM100
TMEM120B
TMEM128
TMEM140
TMEM14B
TMEM14C
TMEM201
TMEM208
TMEM218
TMEM236
TMEM237
TMEM243
TMEM254
TMEM42
TMEM50B
TMEM54
TMEM60
TMEM97
TMPPE
TNFRSF10C
TSNARE1
TSPAN33
TSPAN7
TSPO2
UBIAD1
UNC50
VAMP1
VAMP4
VAMP5
VKORC1
YIPF1
YIPF4
YIPF6
ZDHHC15
Entrez ID
731
390212
HPRD ID
00409
13599
Ensembl ID
ENSG00000157131
ENSG00000175514
Uniprot IDs
P07357
A0A0I9RJ67
Q8TDT2
PDB IDs
2QOS
2QQH
2RD7
3OJY
6H03
6H04
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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