C8A and SLC10A1

Data Source:
BioGRID (two hybrid)

		C8A	SLC10A1
Description		complement C8 alpha chain	solute carrier family 10 member 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Membrane Attack Complex Extracellular Space Membrane Extracellular Exosome Blood Microparticle	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane
	Molecular Function	Complement Binding Protein Binding Protein-containing Complex Binding	Virus Receptor Activity Protein Binding Bile Acid:sodium Symporter Activity
	Biological Process	Immune Response Complement Activation Complement Activation, Alternative Pathway Complement Activation, Classical Pathway Cytolysis Regulation Of Complement Activation	Sodium Ion Transport Regulation Of Gene Expression Bile Acid And Bile Salt Transport Response To Nutrient Levels Cellular Response To Drug Bile Acid Signaling Pathway Response To Ethanol Viral Entry Into Host Cell Transmembrane Transport Regulation Of Bile Acid Secretion Response To 17alpha-ethynylestradiol
Pathways		Terminal pathway of complement Regulation of Complement cascade	Recycling of bile acids and salts
Drugs		Zinc Zinc acetate
Diseases		Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
GWAS		Blood protein levels ( 28240269)	Daytime sleep phenotypes ( 27126917) Metabolite levels ( 23823483) Triglyceride levels ( 30108155)
Interacting Genes		9 interacting genes: C8B C8G C9 CD59 GOLT1A GPR152 MMGT1 SLC10A1 SLC7A1	91 interacting genes: ABHD16A ACSL5 AGPAT3 ARL6IP6 ASGR1 ATP6V0B BMP10 C2 C8A CFHR5 CLDN19 CMTM3 COX20 CXCL9 CYB5R3 DERL1 DGAT2L6 FA2H FAM241B FAXDC2 FCER1G FDFT1 FXYD3 FXYD6 FXYD6-FXYD2 GAST GDE1 GIMAP5 GOSR2 GPR151 GPR152 IFITM2 IFITM3 IFTAP LRP10 LSS MAL MALL MFSD6 MS4A1 MYADML2 NEU1 NINJ2 ORMDL1 ORMDL2 ORMDL3 OTOP3 PEDS1-UBE2V1 PEX16 PKMYT1 RUSF1 SACM1L SCAMP4 SELENOK SFT2D1 SFT2D2 SFXN1 SLC12A7 SLC16A13 SLC25A46 SLC29A2 SLC35E4 SLC38A1 SLC38A7 SLC41A1 SLC66A2 SLC7A3 SMPD2 STX7 TAP1 TFRC TMBIM1 TMEM119 TMEM120B TMEM121 TMEM147 TMEM222 TMEM234 TMEM239 TMEM242 TMEM60 TMUB2 TOMM6 TRARG1 TSPO2 TVP23B UNC50 VAMP3 YIF1A YIPF4 YIPF6
Entrez ID		731	6554
HPRD ID		00409	01672
Ensembl ID		ENSG00000157131	ENSG00000100652
Uniprot IDs		P07357	B2RA41 Q14973
PDB IDs		2QOS 2QQH 2RD7 3OJY 6H03 6H04
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?