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TRAF5 and COMMD3
Data Source:
BioGRID
(two hybrid)
TRAF5
COMMD3
Description
TNF receptor associated factor 5
COMM domain containing 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Centrosome
Cytosol
Cytoplasmic Side Of Plasma Membrane
CD40 Receptor Complex
Plasma Membrane Signaling Receptor Complex
Extracellular Region
Nucleus
Ficolin-1-rich Granule Lumen
Molecular Function
Ubiquitin-protein Transferase Activity
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Binding
Thioesterase Binding
Identical Protein Binding
Protein Binding
Biological Process
Apoptotic Process
Signal Transduction
Positive Regulation Of Cell Population Proliferation
Tumor Necrosis Factor-mediated Signaling Pathway
Regulation Of Apoptotic Process
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of JNK Cascade
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein K63-linked Ubiquitination
Sodium Ion Transport
Neutrophil Degranulation
Pathways
Neutrophil degranulation
Neddylation
Drugs
Diseases
GWAS
Household income (MTAG) (
31844048
)
Prostate-specific antigen levels (
28139693
)
Interacting Genes
66 interacting genes:
BEX3
CAPNS1
CCDC184
CD27
CD40
CDC37
CIB3
COG7
COMMD3
DGKH
ENOX2
FAM9A
FBXO28
GAS8
GOLGA2
GORASP2
HOMER1
HSD17B10
HSF2BP
LMO4
LNX1
LTBR
MAP3K14
MAP3K5
MDM2
MEOX2
NMI
NTAQ1
NUMBL
ODF2
PIAS2
PIBF1
PICK1
PSMA1
RAD23A
RIPK1
RIPK2
RNF111
RNF4
SDCBP
SEC13
SERPINB9
SUMO1
TBK1
TDP2
THAP1
THAP7
TNFRSF11A
TNFRSF12A
TNFRSF13B
TNFRSF14
TNFRSF19
TNFRSF4
TNFRSF8
TRAF2
TRAF3
TRAF3IP2
TRAF6
TRIM27
TRIM37
TRIM8
UBC
USP7
YPEL5
ZFAND6
ZNF655
5 interacting genes:
COMMD1
COMMD2
PIH1D2
TRAF5
ZNF337
Entrez ID
7188
23412
HPRD ID
03834
13082
Ensembl ID
ENSG00000082512
ENSG00000148444
Uniprot IDs
O00463
Q9UBI1
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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