COMMD3 and TRAF5

Data Source:
BioGRID (two hybrid)

		COMMD3	TRAF5
Description		COMM domain containing 3	TNF receptor associated factor 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Ficolin-1-rich Granule Lumen	Centrosome Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex Plasma Membrane Signaling Receptor Complex
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thioesterase Binding Identical Protein Binding
	Biological Process	Sodium Ion Transport Neutrophil Degranulation	Apoptotic Process Signal Transduction Positive Regulation Of Cell Population Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of JNK Cascade Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein K63-linked Ubiquitination
Pathways		Neutrophil degranulation Neddylation
Drugs
Diseases
GWAS		Prostate-specific antigen levels ( 28139693)	Household income (MTAG) ( 31844048)
Interacting Genes		5 interacting genes: COMMD1 COMMD2 PIH1D2 TRAF5 ZNF337	66 interacting genes: BEX3 CAPNS1 CCDC184 CD27 CD40 CDC37 CIB3 COG7 COMMD3 DGKH ENOX2 FAM9A FBXO28 GAS8 GOLGA2 GORASP2 HOMER1 HSD17B10 HSF2BP LMO4 LNX1 LTBR MAP3K14 MAP3K5 MDM2 MEOX2 NMI NTAQ1 NUMBL ODF2 PIAS2 PIBF1 PICK1 PSMA1 RAD23A RIPK1 RIPK2 RNF111 RNF4 SDCBP SEC13 SERPINB9 SUMO1 TBK1 TDP2 THAP1 THAP7 TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF14 TNFRSF19 TNFRSF4 TNFRSF8 TRAF2 TRAF3 TRAF3IP2 TRAF6 TRIM27 TRIM37 TRIM8 UBC USP7 YPEL5 ZFAND6 ZNF655
Entrez ID		23412	7188
HPRD ID		13082	03834
Ensembl ID		ENSG00000148444	ENSG00000082512
Uniprot IDs		Q9UBI1	O00463
PDB IDs
Enriched GO Terms of Interacting Partners?
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