TRAF5 and COG7

Data Source:
BioGRID (affinity chromatography technology, pull down)

		TRAF5	COG7
Description		TNF receptor associated factor 5	component of oligomeric golgi complex 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex Plasma Membrane Signaling Receptor Complex	Golgi Membrane Nucleolus Golgi Apparatus Golgi Transport Complex Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thioesterase Binding Identical Protein Binding	Protein Binding
	Biological Process	Apoptotic Process Signal Transduction Positive Regulation Of Cell Population Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of JNK Cascade Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein K63-linked Ubiquitination	Protein Glycosylation Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Protein Localization To Organelle Protein Localization To Golgi Apparatus Protein Stabilization
Pathways			COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type II
GWAS		Household income (MTAG) ( 31844048)	Egg allergy ( 25710614)
Interacting Genes		66 interacting genes: BEX3 CAPNS1 CCDC184 CD27 CD40 CDC37 CIB3 COG7 COMMD3 DGKH ENOX2 FAM9A FBXO28 GAS8 GOLGA2 GORASP2 HOMER1 HSD17B10 HSF2BP LMO4 LNX1 LTBR MAP3K14 MAP3K5 MDM2 MEOX2 NMI NTAQ1 NUMBL ODF2 PIAS2 PIBF1 PICK1 PSMA1 RAD23A RIPK1 RIPK2 RNF111 RNF4 SDCBP SEC13 SERPINB9 SUMO1 TBK1 TDP2 THAP1 THAP7 TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF14 TNFRSF19 TNFRSF4 TNFRSF8 TRAF2 TRAF3 TRAF3IP2 TRAF6 TRIM27 TRIM37 TRIM8 UBC USP7 YPEL5 ZFAND6 ZNF655	9 interacting genes: COG4 COG5 EMILIN1 HNRNPD KIFC3 MEOX2 TAX1BP1 TRAF5 ZNF471
Entrez ID		7188	91949
HPRD ID		03834	07373
Ensembl ID		ENSG00000082512	ENSG00000168434
Uniprot IDs		O00463	A0A0S2Z652 P83436
PDB IDs
Enriched GO Terms of Interacting Partners?
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