C1QC and FKBP2

Data Source:
HPRD (in vitro, two hybrid)

		C1QC	FKBP2
Description		complement C1q C chain	FKBP prolyl isomerase 2
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GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Synapse Collagen-containing Extracellular Matrix Blood Microparticle Postsynapse	Endoplasmic Reticulum Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding
	Biological Process	Immune Response Complement Activation Complement Activation, Classical Pathway Regulation Of Complement Activation Negative Regulation Of Granulocyte Differentiation Innate Immune Response Negative Regulation Of Macrophage Differentiation Synapse Pruning	Protein Peptidyl-prolyl Isomerization
Pathways		Initial triggering of complement Classical antibody-mediated complement activation Regulation of Complement cascade
Drugs		Cetuximab Etanercept Palivizumab Daclizumab Bevacizumab Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases		Classic complement pathway component defects, including the following eight diseases: C1q alpha-chain deficiency; C1q beta-chain deficiency; C1q gamma-chain deficiency; C1r deficiency; C1s deficiency; C2 deficiency; C3 deficiency; C4 deficiency
GWAS		Blood protein levels ( 30072576 29875488)	Crohn's disease ( 28067908) Fruit consumption ( 32066663)
Interacting Genes		6 interacting genes: C1QA C1QB FKBP2 PTX3 UBQLN2 ZNF534	14 interacting genes: ARFGEF1 BAG6 BARD1 C1QC EPB41 EPB41L2 MAPK3 RAB3C RAB6A RAP2A UBQLN1 UBQLN2 UBQLN4 VAMP2
Entrez ID		714	2286
HPRD ID		00395	01742
Ensembl ID		ENSG00000159189	ENSG00000173486
Uniprot IDs		A0A024RAA7 P02747	P26885 Q53XJ5
PDB IDs		1PK6 2JG8 2JG9 2WNU 2WNV 5HKJ 5HZF 6FCZ 6Z6V	2PBC 4NNR
Enriched GO Terms of Interacting Partners?
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