C1QC

Description		complement C1q C chain
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GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Synapse Collagen-containing Extracellular Matrix Blood Microparticle Postsynapse
	Molecular Function	Protein Binding
	Biological Process	Immune Response Complement Activation Complement Activation, Classical Pathway Regulation Of Complement Activation Negative Regulation Of Granulocyte Differentiation Innate Immune Response Negative Regulation Of Macrophage Differentiation Synapse Pruning
Pathways		Initial triggering of complement Classical antibody-mediated complement activation Regulation of Complement cascade
Drugs		Cetuximab Etanercept Palivizumab Daclizumab Bevacizumab Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases		Classic complement pathway component defects, including the following eight diseases: C1q alpha-chain deficiency; C1q beta-chain deficiency; C1q gamma-chain deficiency; C1r deficiency; C1s deficiency; C2 deficiency; C3 deficiency; C4 deficiency
GWAS		Blood protein levels ( 30072576 29875488)
Novel Interacting Genes		1 novel interacting genes: RALA
Interacting Genes		6 interacting genes: C1QA C1QB FKBP2 PTX3 UBQLN2 ZNF534
Entrez ID		714
HPRD ID		00395
Ensembl ID		ENSG00000159189
Uniprot IDs		A0A024RAA7 P02747
PDB IDs		1PK6 2JG8 2JG9 2WNU 2WNV 5HKJ 5HZF 6FCZ 6Z6V
Enriched GO Terms of Interacting Partners?
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