TFF1 and VSNL1

Data Source:
BioGRID (two hybrid)

		TFF1	VSNL1
Description		trefoil factor 1	visinin like 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cytosol Membrane
	Molecular Function	Protein Binding Growth Factor Activity	Calcium Ion Binding Protein Binding
	Biological Process	Carbohydrate Metabolic Process Signal Transduction Negative Regulation Of Cell Population Proliferation Response To Iron Ion Cell Differentiation Maintenance Of Gastrointestinal Epithelium Response To Immobilization Stress Response To Peptide Hormone	Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Exocytosis Negative Regulation Of Insulin Secretion
Pathways		Estrogen-dependent gene expression
Drugs		Raloxifene Afimoxifene
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Pancreatic cancer ( 22158540)	Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Energy expenditure ( 30071075) Psychosis and Alzheimer's disease ( 22005930) Response to fenofibrate (total cholesterol levels) ( 27002377) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		20 interacting genes: AKT1 APC ATM BTN3A1 BTNL8 CD300LD ESR2 FCRL4 FGFR2 GKN2 MUC6 RAD51 SGTB SIGLEC8 TSG101 UBQLN1 UBQLN4 VSNL1 XRCC3 ZNF250	17 interacting genes: ACTB ATXN1 C1QTNF2 CDSN CHRNA4 COL10A1 DTX2 ENDOD1 FAM131C GFI1B LITAF SPRED1 SPRED2 SPRY3 SRL TEX13B TFF1
Entrez ID		7031	7447
HPRD ID		00219	02890
Ensembl ID		ENSG00000160182	ENSG00000163032
Uniprot IDs		P04155	P62760
PDB IDs		1HI7 1PS2 6V1D
Enriched GO Terms of Interacting Partners?
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