VSNL1 and COL10A1

Data Source:
BioGRID (two hybrid)

		VSNL1	COL10A1
Description		visinin like 1	collagen type X alpha 1 chain
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane	Extracellular Region Collagen Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Calcium Ion Binding Protein Binding	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength Metal Ion Binding
	Biological Process	Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Exocytosis Negative Regulation Of Insulin Secretion	Skeletal System Development Extracellular Matrix Organization
Pathways			Collagen degradation Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Non-integrin membrane-ECM interactions Collagen chain trimerization
Drugs
Diseases			Metaphyseal dysplasias, including: Metaphyseal dysplasia, Schmid type; Metaphyseal dysplasia, McKusik type; Metaphyseal dysplasia, Jansen type; Shwachman-Bodian-Diamond syndrome (SBDS); Metaphyseal anadysplasia (MAD)
GWAS		Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Energy expenditure ( 30071075) Psychosis and Alzheimer's disease ( 22005930) Response to fenofibrate (total cholesterol levels) ( 27002377) Squamous cell lung carcinoma ( 28604730)	Age-related macular degeneration ( 23455636 21665990) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Myopia ( 27182965) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		17 interacting genes: ACTB ATXN1 C1QTNF2 CDSN CHRNA4 COL10A1 DTX2 ENDOD1 FAM131C GFI1B LITAF SPRED1 SPRED2 SPRY3 SRL TEX13B TFF1	10 interacting genes: ANXA5 BANP CIDEB MESD NRF1 P4HB SGTB UBQLN1 UBQLN2 VSNL1
Entrez ID		7447	1300
HPRD ID		02890	00357
Ensembl ID		ENSG00000163032	ENSG00000123500
Uniprot IDs		P62760	A0A650AXN9 Q03692
PDB IDs			1GR3
Enriched GO Terms of Interacting Partners?
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