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BUB1B and TRIP13
Data Source:
BioGRID
(pull down)
BUB1B
TRIP13
Description
BUB1 mitotic checkpoint serine/threonine kinase B
thyroid hormone receptor interactor 13
Image
GO Annotations
Cellular Component
Kinetochore
Condensed Chromosome Kinetochore
Condensed Nuclear Chromosome Kinetochore
Condensed Chromosome Outer Kinetochore
Anaphase-promoting Complex
Cytoplasm
Microtubule Organizing Center
Spindle
Cytosol
Perinuclear Region Of Cytoplasm
Male Germ Cell Nucleus
Nucleus
Chromosome
Molecular Function
Protein Kinase Activity
Protein Binding
ATP Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Transcription Coregulator Activity
Protein Binding
ATP Binding
ATPase Activity
Identical Protein Binding
Biological Process
Mitotic Cell Cycle
Protein Phosphorylation
Ubiquitin-dependent Protein Catabolic Process
Apoptotic Process
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Checkpoint
Mitotic Spindle Assembly Checkpoint
Anaphase-promoting Complex-dependent Catabolic Process
Cell Division
Meiotic Sister Chromatid Cohesion, Centromeric
Protein Localization To Chromosome, Centromeric Region
Regulation Of Mitotic Cell Cycle Phase Transition
Oocyte Maturation
Double-strand Break Repair
Regulation Of Transcription, DNA-templated
Transcription By RNA Polymerase II
Mitotic Spindle Assembly Checkpoint
Synaptonemal Complex Assembly
Reciprocal Meiotic Recombination
Male Meiosis I
Female Meiosis I
Spermatogenesis
Spermatid Development
Oogenesis
Meiotic Recombination Checkpoint
Pathways
Inactivation of APC/C via direct inhibition of the APC/C complex
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
APC/C:Cdc20 mediated degradation of mitotic proteins
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Chronic lymphocytic leukemia (
28165464
24292274
)
Pancreatic cancer (
25086665
)
Interacting Genes
26 interacting genes:
ANAPC7
AP1B1
AP2B1
AP3B1
AP4B1
APC
BRCA2
BUB3
CCNA2
CDC16
CDC20
CDC27
CENPE
COMMD4
DNMBP
FBXO7
FZR1
HDAC1
KNL1
MAP3K4
PELI1
PLK1
RIPK3
SNCG
TP73
TRIP13
112 interacting genes:
ADAM15
AMDHD2
ANKRD10
ARL11
ARSA
ASB13
BUB1B
C11orf54
C19orf54
C4orf33
CARD14
CD99
CDC20
CDIN1
CEP170B
CFP
CLIP4
COMT
CRMP1
CRYBA2
CYB5R2
DCTN3
DDAH2
DIP2A
DPYSL4
DTX2
EEF2KMT
FBLN5
FBXO8
FNDC3B
GALT
GLYCTK
GPRIN2
GPSM1
HDHD3
IGFN1
IL2RB
INCA1
INTS11
KRTAP12-1
KRTAP12-2
KRTAP12-4
KRTAP26-1
KRTAP3-2
KRTAP6-1
KRTAP6-2
KYAT1
LASP1
LNX1
LOXL4
LRR1
LRRC61
M1AP
MAD2L1
MAD2L1BP
MBLAC1
MEAK7
METTL15
MGAT5B
MORN3
MPPED2
MVP
MYEOV
NIF3L1
NME4
NTAQ1
PARP11
PAX9
PBLD
PCMTD2
PCSK5
PELI1
PLAC8
PLK3
PLSCR3
PLSCR4
POLR2L
PPP2CA
PRKAA2
PRKN
PRR13
PSMB8
QARS1
RBPMS
RHOXF2
RNF4
SCP2
SDCBP
SEC24A
SELENBP1
SEMA3B
SEMA4G
SHARPIN
SIGLEC5
SMUG1
SPRYD7
SSC4D
STAMBP
STAMBPL1
SUMO2
TENT5B
TEX37
THRB
TINAGL1
TNRC6A
TPT1
UBE2I
VDR
VENTX
ZMYM5
ZNF34
ZNF655
Entrez ID
701
9319
HPRD ID
04176
05145
Ensembl ID
ENSG00000156970
ENSG00000071539
Uniprot IDs
O60566
Q15645
PDB IDs
2WVI
3SI5
4GGD
5JJA
5K6S
5KHU
5LCW
5SWF
6TLJ
5VQ9
5VQA
5WC2
6F0X
6LK0
Enriched GO Terms of Interacting Partners
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