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BUB1B and DNMBP
Data Source:
BioGRID
(two hybrid)
BUB1B
DNMBP
Description
BUB1 mitotic checkpoint serine/threonine kinase B
dynamin binding protein
Image
GO Annotations
Cellular Component
Kinetochore
Condensed Chromosome Kinetochore
Condensed Nuclear Chromosome Kinetochore
Condensed Chromosome Outer Kinetochore
Anaphase-promoting Complex
Cytoplasm
Microtubule Organizing Center
Spindle
Cytosol
Perinuclear Region Of Cytoplasm
Golgi Apparatus
Golgi Stack
Cytoskeleton
Cell-cell Junction
Synapse
Presynapse
Molecular Function
Protein Kinase Activity
Protein Binding
ATP Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Biological Process
Mitotic Cell Cycle
Protein Phosphorylation
Ubiquitin-dependent Protein Catabolic Process
Apoptotic Process
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Checkpoint
Mitotic Spindle Assembly Checkpoint
Anaphase-promoting Complex-dependent Catabolic Process
Cell Division
Meiotic Sister Chromatid Cohesion, Centromeric
Protein Localization To Chromosome, Centromeric Region
Regulation Of Mitotic Cell Cycle Phase Transition
Aging
Regulation Of Cell Shape
Intracellular Signal Transduction
Regulation Of Catalytic Activity
Pathways
Inactivation of APC/C via direct inhibition of the APC/C complex
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
APC/C:Cdc20 mediated degradation of mitotic proteins
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Chronic lymphocytic leukemia (
28165464
24292274
)
Stent thrombosis in response to clopidogrel treatment (
32472697
)
Interacting Genes
26 interacting genes:
ANAPC7
AP1B1
AP2B1
AP3B1
AP4B1
APC
BRCA2
BUB3
CCNA2
CDC16
CDC20
CDC27
CENPE
COMMD4
DNMBP
FBXO7
FZR1
HDAC1
KNL1
MAP3K4
PELI1
PLK1
RIPK3
SNCG
TP73
TRIP13
20 interacting genes:
ACTA1
ARHGAP17
BUB1B
CDC42
CNN1
CYFIP2
DBN1
DNM1
ENAH
EVL
FASLG
HSPA1B
KHDRBS1
NCKAP1
RAC1
RAPH1
VASP
WASF1
WASL
WIPF2
Entrez ID
701
23268
HPRD ID
04176
10918
Ensembl ID
ENSG00000156970
ENSG00000107554
Uniprot IDs
O60566
A0A1B0GTX1
A0A1C7CYY6
B3KY33
Q6XZF7
PDB IDs
2WVI
3SI5
4GGD
5JJA
5K6S
5KHU
5LCW
5SWF
6TLJ
1UG1
1UHC
4CC2
4CC3
4CC4
4CC7
4GLM
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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