TEAD1 and BORCS8-MEF2B

Data Source:
HPRD (in vitro)

		TEAD1	BORCS8-MEF2B
Description		TEA domain transcription factor 1	BORCS8-MEF2B readthrough
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GO Annotations	Cellular Component	Chromatin Nucleoplasm Transcription Regulator Complex TEAD-YAP Complex	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytosol Cell Junction
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Histone Deacetylase Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Hippo Signaling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Protein-containing Complex Assembly Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Muscle Organ Development Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination	Myogenesis
Drugs
Diseases
GWAS		Central retinal vein equivalent ( 26567291) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diisocyanate-induced asthma ( 25918132) Gut microbiota relative abundance (unclassified genus belonging to family Erysipelotrichaceae) ( 33208821) HDL cholesterol levels x loop diuretics use interaction ( 31806883) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103) HOMA-B (corrected for HOMA-IR) ( 30369944) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Neutrophil count ( 32888494)	Height ( 28552196)
Interacting Genes		21 interacting genes: BORCS8-MEF2B ENO1 GCAT HLA-DMB INSR MAX MEF2A MEF2C MYH7 NCOA1 SRF TBP TRIM3 UBTD1 VGLL1 VGLL2 VGLL3 VGLL4 WWTR1 YAP1 ZDHHC17	9 interacting genes: AGR2 CABIN1 CTAG1A CTAG1B HDAC4 MESD TEAD1 TEKT4 TEX11
Entrez ID		7003	4207
HPRD ID		01802	02808
Ensembl ID		ENSG00000187079	ENSG00000213999
Uniprot IDs		P28347 Q59EF3	A0A024R7N0 Q02080
PDB IDs		2HZD 3KYS 4RE1 4Z8E 5NNX 6HIL 6IM5	1N6J 1TQE 6BYY 6BZ1 6C9L 6WC2 6WC5
Enriched GO Terms of Interacting Partners?
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