TAF10 and TAF1

Data Source:
HPRD (in vivo, in vitro)

		TAF10	TAF1
Description		TATA-box binding protein associated factor 10	TATA-box binding protein associated factor 1
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GO Annotations	Cellular Component	PCAF Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytoplasm STAGA Complex Transcription Factor TFTC Complex Perinuclear Region Of Cytoplasm	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Transcription Factor TFIID Complex Nucleolus MLL1 Complex
	Molecular Function	DNA Binding Histone Acetyltransferase Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Enzyme Binding Estrogen Receptor Binding Identical Protein Binding RNA Polymerase Binding Promoter-specific Chromatin Binding	RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase I General Transcription Initiation Factor Activity P53 Binding Histone Acetyltransferase Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity Kinase Activity TBP-class Protein Binding Nuclear Hormone Receptor Binding Sequence-specific DNA Binding Protein Heterodimerization Activity H3K27me3 Modified Histone Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Ubiquitin Conjugating Enzyme Activity Lysine-acetylated Histone Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity Transcription Regulator Inhibitor Activity Acetyl-CoA Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Apoptotic Process Regulation Of Gene Expression Histone Deubiquitination Protein Deubiquitination Cellular Protein-containing Complex Assembly Multicellular Organism Growth Histone H3 Acetylation Regulation Of DNA Binding Hepatocyte Differentiation Regulation Of Signal Transduction By P53 Class Mediator	Negative Regulation Of Transcription By RNA Polymerase II Protein Polyubiquitination Transcription Initiation From RNA Polymerase I Promoter Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Phosphorylation Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Cell Cycle Negative Regulation Of Gene Expression Viral Process Histone Acetylation Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Midbrain Development Positive Regulation Of Protein Binding Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To UV Transcription Factor Catabolic Process Negative Regulation Of DNA-binding Transcription Factor Activity Protein Autophosphorylation Protein Stabilization RNA Polymerase II Preinitiation Complex Assembly Cellular Response To ATP Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Negative Regulation Of Protein Autoubiquitination Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Androgen Receptor Activity
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones Ub-specific processing proteases RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Malaria ( 31844061)
Interacting Genes		23 interacting genes: ATXN7 ESR1 FANCA FTL H3-4 POLR2A PSMC5 SETD7 SUPT7L TAF1 TAF11 TAF12 TAF13 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I	57 interacting genes: APC AR ASF1A ASF1B BRMS1 CCNA2 CCND1 CDC42BPA CLIP4 DNAJB5 DOCK9 DYSF EDF1 EWSR1 FOS GFI1B GTF2A1 GTF2E1 GTF2F1 H1-1 H3-4 HMGB1 HSF1 ITGB5 JUN LHX3 MAX MDM2 MSX1 MYOM2 PAX3 PRKD3 RANBP2 RB1 RBL1 RBL2 RELA SGCA SPTAN1 SUB1 SUMO2 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF4B TAF5 TAF6 TAF7 TAF8 TAF9 TBP TP53 UBE2I UBTF
Entrez ID		6881	6872
HPRD ID		15972	02436
Ensembl ID		ENSG00000166337	ENSG00000147133
Uniprot IDs		Q12962	P21675
PDB IDs		2F69 3M53 3M54 3M55 3M56 3M57 3M58 3M59 3M5A 4J7F 4J7I 4J83 4J8O 4WV4 5EG2 6MZC 6MZD 6MZL 6MZM	1EQF 3AAD 3UV4 3UV5 4RGW 4YYM 4YYN 5FUR 5I1Q 5I29 5MG2 6BQD 6FIC 6MZD 6MZL 6MZM 6P38 6P39 6P3A
Enriched GO Terms of Interacting Partners?
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