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TAF1 and HSF1
Data Source:
HPRD
(in vitro)
TAF1
HSF1
Description
TATA-box binding protein associated factor 1
heat shock transcription factor 1
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Transcription Factor TFIID Complex
Nucleolus
MLL1 Complex
Kinetochore
Condensed Chromosome Kinetochore
Chromatin
Euchromatin
Heterochromatin
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
PML Body
Perinuclear Region Of Cytoplasm
Nuclear Stress Granule
Mitotic Spindle Pole
Chaperone Complex
Ribonucleoprotein Complex
Molecular Function
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
RNA Polymerase I General Transcription Initiation Factor Activity
P53 Binding
Histone Acetyltransferase Activity
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Transcription Factor Binding
RNA Polymerase II General Transcription Initiation Factor Activity
Kinase Activity
TBP-class Protein Binding
Nuclear Hormone Receptor Binding
Sequence-specific DNA Binding
Protein Heterodimerization Activity
H3K27me3 Modified Histone Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Ubiquitin Conjugating Enzyme Activity
Lysine-acetylated Histone Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Transcription Regulator Inhibitor Activity
Acetyl-CoA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Protein Kinase Binding
Heat Shock Protein Binding
Chromatin DNA Binding
Identical Protein Binding
Sequence-specific DNA Binding
Protein Self-association
Protein Heterodimerization Activity
Hsp90 Protein Binding
Translation Elongation Factor Binding
STAT Family Protein Binding
Sequence-specific Single Stranded DNA Binding
Sequence-specific Double-stranded DNA Binding
Promoter-specific Chromatin Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Protein Polyubiquitination
Transcription Initiation From RNA Polymerase I Promoter
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Protein Phosphorylation
Ubiquitin-dependent Protein Catabolic Process
Cellular Response To DNA Damage Stimulus
Cell Cycle
Negative Regulation Of Gene Expression
Viral Process
Histone Acetylation
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Midbrain Development
Positive Regulation Of Protein Binding
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To UV
Transcription Factor Catabolic Process
Negative Regulation Of DNA-binding Transcription Factor Activity
Protein Autophosphorylation
Protein Stabilization
RNA Polymerase II Preinitiation Complex Assembly
Cellular Response To ATP
Regulation Of Signal Transduction By P53 Class Mediator
Regulation Of Cell Cycle G1/S Phase Transition
Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Negative Regulation Of Protein Autoubiquitination
Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Androgen Receptor Activity
Negative Regulation Of Transcription By RNA Polymerase II
MAPK Cascade
DNA Repair
Regulation Of Transcription By RNA Polymerase II
MRNA Processing
Defense Response
Response To Nutrient
Positive Regulation Of Cell Population Proliferation
MRNA Transcription
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Response To Activity
Viral Process
Negative Regulation Of Protein-containing Complex Assembly
Response To Testosterone
Cellular Response To Heat
Cellular Response To Unfolded Protein
Cellular Protein-containing Complex Assembly
Cellular Response To Potassium Ion
Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Mitotic Cell Cycle
Positive Regulation Of Transcription By RNA Polymerase II
MRNA Transport
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Heat Stress
Cellular Response To Hydrogen Peroxide
Cellular Response To Lipopolysaccharide
Cellular Response To Cadmium Ion
Cellular Response To Copper Ion
Cellular Response To Estradiol Stimulus
Cellular Response To Gamma Radiation
Cellular Response To Diamide
Negative Regulation Of Inclusion Body Assembly
Positive Regulation Of Inclusion Body Assembly
Positive Regulation Of Cold-induced Thermogenesis
Regulation Of Cellular Response To Heat
Positive Regulation Of MRNA Polyadenylation
Negative Regulation Of Neuron Death
Positive Regulation Of Apoptotic DNA Fragmentation
Cellular Response To Sodium Arsenite
Cellular Response To Angiotensin
Positive Regulation Of Microtubule Binding
Cellular Response To Nitroglycerin
Cellular Response To L-glutamine
Response To Hypobaric Hypoxia
Response To Psychosocial Stress
Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
RNA Polymerase II Pre-transcription Events
Regulation of TP53 Activity through Phosphorylation
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance
Regulation of HSF1-mediated heat shock response
HSF1 activation
Attenuation phase
HSF1-dependent transactivation
Aggrephagy
Drugs
Bimoclomol
Diseases
GWAS
Dupuytren's disease (
28886342
)
Interacting Genes
57 interacting genes:
APC
AR
ASF1A
ASF1B
BRMS1
CCNA2
CCND1
CDC42BPA
CLIP4
DNAJB5
DOCK9
DYSF
EDF1
EWSR1
FOS
GFI1B
GTF2A1
GTF2E1
GTF2F1
H1-1
H3-4
HMGB1
HSF1
ITGB5
JUN
LHX3
MAX
MDM2
MSX1
MYOM2
PAX3
PRKD3
RANBP2
RB1
RBL1
RBL2
RELA
SGCA
SPTAN1
SUB1
SUMO2
TAF10
TAF11
TAF12
TAF15
TAF2
TAF4
TAF4B
TAF5
TAF6
TAF7
TAF8
TAF9
TBP
TP53
UBE2I
UBTF
51 interacting genes:
CAMK2A
CDC20
CDK6
CEBPB
CHST10
CREBBP
CSNK2A1
DAXX
DNAJB1
EEF1D
ENO2
FILIP1
FKBP4
FKBP5
GSK3A
GTF2A2
GTF2B
HSBP1
HSF2
HSP90AA1
HSP90AB1
HSPA1A
HSPA8
MAPK1
MAPK3
MAPK8
MAPK9
MAPKAPK2
NCOA6
PIM2
PPID
PRKDC
PTGES3
RALBP1
REPS1
RNF20
SMARCA4
STAT1
STUB1
SUB1
SUMO1
SUMO3
SYMPK
TAF1
TAF7
TAF9
TBP
UBE2I
XRCC5
XRCC6
YWHAE
Entrez ID
6872
3297
HPRD ID
02436
00778
Ensembl ID
ENSG00000147133
ENSG00000185122
Uniprot IDs
P21675
Q00613
PDB IDs
1EQF
3AAD
3UV4
3UV5
4RGW
4YYM
4YYN
5FUR
5I1Q
5I29
5MG2
6BQD
6FIC
6MZD
6MZL
6MZM
6P38
6P39
6P3A
2LDU
5D5U
5D5V
5HDG
5HDN
Enriched GO Terms of Interacting Partners
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