TAF5 and TAF2

Data Source:
HPRD (in vivo, in vitro)

		TAF5	TAF2
Description		TATA-box binding protein associated factor 5	TATA-box binding protein associated factor 2
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Factor TFIID Complex Nucleolus Actin Cytoskeleton Transcription Factor TFTC Complex	Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFTC Complex
	Molecular Function	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Identical Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity
	Biological Process	DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Viral Process SnRNA Transcription By RNA Polymerase II Histone H3 Acetylation Regulation Of Signal Transduction By P53 Class Mediator	G2/M Transition Of Mitotic Cell Cycle Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Response To Organic Cyclic Compound Regulation Of Signal Transduction By P53 Class Mediator
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Height ( 31562340) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 25056061 23974872)	Heart rate response to exercise ( 29769521)
Interacting Genes		16 interacting genes: CPSF1 GTF2F2 H3-4 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF6 TAF7 TAF8 TAF9 TBP UBE2I	14 interacting genes: ESR1 H3-4 PUF60 RNPS1 TAF1 TAF10 TAF11 TAF12 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9
Entrez ID		6877	6873
HPRD ID		11876	07060
Ensembl ID		ENSG00000148835	ENSG00000064313
Uniprot IDs		Q15542	A0A024R9E6 B3KMD8 Q6P1X5
PDB IDs		2NXP 6F3T 6MZC 6MZD 6MZL 6MZM	5FUR 6MZC 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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