TAF2 and TAF4

Data Source:
HPRD (in vitro, in vivo)

		TAF2	TAF4
Description		TATA-box binding protein associated factor 2	TATA-box binding protein associated factor 4
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GO Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFTC Complex	Chromatin Nucleoplasm Transcription Factor TFIID Complex Cytosol Protein-containing Complex Transcription Factor TFTC Complex MLL1 Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity	Core Promoter Sequence-specific DNA Binding DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Aryl Hydrocarbon Receptor Binding Protein Heterodimerization Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Response To Organic Cyclic Compound Regulation Of Signal Transduction By P53 Class Mediator	Ovarian Follicle Development DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Viral Process Regulation Of Signal Transduction By P53 Class Mediator
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Heart rate response to exercise ( 29769521)	Body mass index ( 28892062) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Red blood cell count ( 32888494) Response to fenofibrate (LDL cholesterol levels) ( 27002377)
Interacting Genes		14 interacting genes: ESR1 H3-4 PUF60 RNPS1 TAF1 TAF10 TAF11 TAF12 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9	22 interacting genes: AHR ATF7 CBX3 CBX5 CREM GTF2A1 GTF2A2 H3-4 HTT JUN SP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF5 TAF6 TAF7 TAF8 TAF9 TCF12
Entrez ID		6873	6874
HPRD ID		07060	11797
Ensembl ID		ENSG00000064313	ENSG00000130699
Uniprot IDs		A0A024R9E6 B3KMD8 Q6P1X5	O00268
PDB IDs		5FUR 6MZC 6MZL 6MZM	1H3O 2P6V 6MZC 6MZD 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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