TAF5 and TAF6

Data Source:
BioGRID (biochemical, pull down, affinity chromatography technology, biochemical)
HPRD (in vitro, in vivo)

		TAF5	TAF6
Description		TATA-box binding protein associated factor 5	TATA-box binding protein associated factor 6
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Factor TFIID Complex Nucleolus Actin Cytoskeleton Transcription Factor TFTC Complex	SAGA Complex Nucleoplasm Transcription Factor TFIID Complex Cytosol Protein-containing Complex Transcription Factor TFTC Complex SLIK (SAGA-like) Complex MLL1 Complex
	Molecular Function	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Identical Protein Binding	DNA Binding Transcription Coactivator Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Aryl Hydrocarbon Receptor Binding Protein Heterodimerization Activity
	Biological Process	DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Viral Process SnRNA Transcription By RNA Polymerase II Histone H3 Acetylation Regulation Of Signal Transduction By P53 Class Mediator	DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Apoptotic Process Histone Acetylation SnRNA Transcription By RNA Polymerase II Negative Regulation Of Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Signal Transduction By P53 Class Mediator
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Height ( 31562340) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 25056061 23974872)	Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		16 interacting genes: CPSF1 GTF2F2 H3-4 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF6 TAF7 TAF8 TAF9 TBP UBE2I	25 interacting genes: AHR APP BANP CIITA GTF2E1 H3-4 HNF4A NCOR1 NFYA NFYB NFYC NR1D2 PIH1D2 RELA SH3KBP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF7 TAF8 TAF9
Entrez ID		6877	6878
HPRD ID		11876	11807
Ensembl ID		ENSG00000148835	ENSG00000106290
Uniprot IDs		Q15542	A4D299 P49848
PDB IDs		2NXP 6F3T 6MZC 6MZD 6MZL 6MZM	5FUR 6F3T 6MZC 6MZD 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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