TAF2 and TAF8

Data Source:
HPRD (in vivo, in vitro)

		TAF2	TAF8
Description		TATA-box binding protein associated factor 2	TATA-box binding protein associated factor 8
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GO Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFTC Complex	Nucleus Nucleoplasm Transcription Factor TFIID Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Response To Organic Cyclic Compound Regulation Of Signal Transduction By P53 Class Mediator	DNA-templated Transcription Open Complex Formation Inner Cell Mass Cell Proliferation Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation SnRNA Transcription By RNA Polymerase II Regulation Of Fat Cell Differentiation Maintenance Of Protein Location In Nucleus
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Heart rate response to exercise ( 29769521)	Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (number of eye fixations) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (responsive search score) ( 26242244) HDL cholesterol levels ( 28334899) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		14 interacting genes: ESR1 H3-4 PUF60 RNPS1 TAF1 TAF10 TAF11 TAF12 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9	13 interacting genes: H3-4 KPNA2 KPNB1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF6 TAF7 TAF9
Entrez ID		6873	129685
HPRD ID		07060	18167
Ensembl ID		ENSG00000064313	ENSG00000137413
Uniprot IDs		A0A024R9E6 B3KMD8 Q6P1X5	Q7Z7C8
PDB IDs		5FUR 6MZC 6MZL 6MZM	4WV4 4WV6 5FUR 6MZC 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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